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Invitrogen™ Human FEM1A (aa 231-300) Control Fragment Recombinant Protein

Catalog No. RP107265
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100 μL
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RP107265 100 μL
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Catalog No. RP107265 Supplier Invitrogen™ Supplier No. RP107265
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Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (57%), Rat (57%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66607 (PA5-66607. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

FEM1A (FEM-1 homolog a), also known as EPRAP (Prostaglandin E receptor 4-associated protein), is a 669 amino acid cytoplasmic protein that belongs to the FEM-1 family. FEM1A is present in atheromata and in macrophages derived from peripheral blood monocytes. FEM1A may be a component of an E3 ubiquitin-protein ligase complex and functions as a substrate recognition subunit. It is suggested that FEM1A participates in anti-inflammatory signaling of macrophages via its interaction with EP4. FEM1A is down-regulated in Rhabdomyosarcoma, the most common soft tissue neoplasm of children. FEM1A is considered a candidate gene for polycystic ovary syndrome.

Specifications

Accession Number Q9BSK4
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 55527
Name Human FEM1A (aa 231-300) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias AW611390; DKFZp762M136; EPRAP; fem-1 homolog A; fem-1 homolog a (C. elegans); Fem1a; Fem1aa; FEM1a-A; FEM1-alpha; FEM1-alpha-A; feminization 1 homolog a; feminization 1 homolog a (C. elegans); prostaglandin E receptor 4-associated protein; Protein fem-1 homolog A; protein fem-1 homolog A-A; similar to fem-1 homolog a (C.elegans)
Common Name FEM1A
Gene Symbol FEM1A
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence VEYLIQEQPGQEQVAGGEAQPGLPQEDPSTSQGCAQPQGAPCCSSSPEEPLNGESYESCCPTSREAAVEA
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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