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Invitrogen™ Human EVER2 Synthetic Peptide

Catalog No. PEP0646
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50 μg
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Catalog No. Quantity
PEP0646 50 μg
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Catalog No. PEP0646 Supplier Invitrogen™ Supplier No. PEP0646

Synthetic Peptide

This peptide corresponds to 14 amino acids near the center of human EVER2. PEP-0646 can be used as a blocking peptide with polyclonal antibody PA5-20526.

Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc.

Specifications

Species Human
Purification Method purified
Accession Number Q8IU68
Common Name EVER2
Concentration 200 μg/mL
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Alias epidermodysplasia verruciformis 2; epidermodysplasia verruciformis protein 2; Epidermodysplasia verruciformis protein 2 homolog; EV2; Ever2; EVIN2; mFLJ00400; Tmc8; transmembrane channel like 8; transmembrane channel-like 8; transmembrane channel-like gene family 8; transmembrane channel-like protein 8
Gene Symbol TMC8
Lyophilized No
Preservative Sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
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