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Invitrogen™ Human EPC1 (aa 717-798) Control Fragment Recombinant Protein

Catalog No. RP109888
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100 μL
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RP109888 100 μL
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Catalog No. RP109888 Supplier Invitrogen™ Supplier No. RP109888
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-145011 (PA5-145011. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.

Specifications

Accession Number Q9H2F5
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 80314
Name Human EPC1 (aa 717-798) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 2400007E14Rik; 5730566F07Rik; A930032N02Rik; DKFZp781P2312; enhancer of polycomb 1; enhancer of polycomb homolog 1; enhancer of polycomb homolog 1 (Drosophila); Epc1; Epl 1; Epl1; mir-1893
Common Name EPC1
Gene Symbol EPC1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SALLQPSNITQTSSSHSALSHQVTAANSATTQVLIGNNIRLTVPSSVATVNSIAPINARHIPRTLSAVPSSALKLAAAANCQ
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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