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Invitrogen™ Human EFTUD1 Control Fragment Recombinant Protein

Catalog No. RP99503
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100 μL
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RP99503 100 μL
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Catalog No. RP99503 Supplier Invitrogen™ Supplier No. RP99503
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62590 (PA5-62590. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

EFTUD1 is involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.

Specifications

Accession Number Q7Z2Z2
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 79631
Name Human EFTUD1 Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 4932434J20Rik; 6030468D11Rik; AI451340; AU019507; AU022896; D7Ertd791e; Efl1; Eftud1; elongation factor like GTPase 1; elongation factor Tu GTP binding domain containing 1; elongation factor Tu GTP-binding domain-containing protein 1; Elongation factor-like 1; elongation factor-like GTPase 1; FAM42A; HsT19294; Protein FAM42A; RIA1; ribosome assembly 1 homolog
Common Name EFTUD1
Gene Symbol Efl1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence TTLADCLISSNGIISSHLAGKLRYMD
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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