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Invitrogen™ Human CISD2 Synthetic Peptide

Numéro de catalogue. PEP1588
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50 μg
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Numéro de catalogue. Quantity
PEP1588 50 μg
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Numéro de catalogue. PEP1588 Fournisseur Invitrogen™ Code fournisseur PEP1588
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Description

Synthetic Peptide

CISD2 Synthetic Peptide, PEP-1588, from Invitrogen.

Defects in the CISD2 (CDGSH iron sulfur domain 2) gene are a cause of the neurodegenerative disorder Wolfram syndrome 2. CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum and mitochondria and binds an iron/sulfur cluster. CISD2 interacts with Bcl-2 and can be displaced by the BH3-only protein BIK and contributes to the regulation of BIK-initiated autophagy. CISD2 deficiency in mice causes mitochondrial breakdown accompanied by autophagic cell death as well as the development of premature aging phenotype.

Spécifications

Gene ID (Entrez) 493856
Species Human
Purification Method purified
Accession Number Q8N5K1
Common Name Human CISD2
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol CISD2
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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