missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Biochemical Reagents
  4. Peptides
  5. PEP0546

Invitrogen™ Human CDNF Synthetic Peptide

Catalog No. PEP0546
Change view
Click to view available options
Quantity:
50 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PEP0546 50 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PEP0546 Supplier Invitrogen™ Supplier No. PEP0546

Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

Description

Synthetic Peptide

This peptide corresponds to 9 amino acids near the carboxy terminus of human CDNF. PEP-0546 can be used as a blocking peptide with polyclonal antibody PA5-20429.

The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6 OHDA) induced degeneration of dopaminergic neurons in a rat model of Parkinsons disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinsons disease. At least two isoforms of CDNF are known to exist.

Specifications

Species Human
Purification Method purified
Accession Number Q49AH0
Common Name CDNF
Concentration 200 μg/mL
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Alias 9330140G23; arginine-rich protein mutated in early stage tumors-like 1; arginine-rich, mutated in early stage tumors-like 1; ARMETL1; ARMET-like protein 1; Cdnf; Cerebral dopamine neurotrophic factor; conserved dopamine neurotrophic factor
Gene Symbol Cdnf
Lyophilized No
Preservative Sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
Show More Show Less