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Invitrogen™ Human ARHGEF18 (aa 983-1050) Control Fragment Recombinant Protein

Catalog No. RP105550
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100 μL
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RP105550 100 μL
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Catalog No. RP105550 Supplier Invitrogen™ Supplier No. RP105550
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Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84879 (PA5-84879. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

Accession Number Q6ZSZ5
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 23370
Name Human ARHGEF18 (aa 983-1050) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 114 kDa Rho-specific guanine nucleotide exchange factor; AI467246; Arhgef18; D030053O22Rik; KIAA0521; p114RhoGEF; P114-RhoGEF; p114-Rho-GEF; rho guanine nucleotide exchange factor 18; rho/rac guanine nucleotide exchange factor (GEF) 18; Rho/Rac guanine nucleotide exchange factor 18; Rho-specific guanine nucleotide exchange factor p114; SA-RhoGEF; Septin-associated RhoGEF
Common Name ARHGEF18
Gene Symbol Arhgef18
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence VLESELVQRIQTLSQLLLNLQAVIAHQDSYVETQRAAIQEREKQFRLQSTRGNLLLEQERQRNFEKQR
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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