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Histamine

Catalog No. p-7042215
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Quantity:
1 g
Catalog No. Quantity
AAJ6172703 1 g
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Catalog No. AAJ6172703

Supplier: Thermo Scientific Chemicals J6172703

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Description

CAS: 51-45-6 | C5H9N3 | 111.15 g/mol

Histamine inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Histamine inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.

Solubility
Soluble in water, alcohol, and hot chloroform.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C Hygroscopic. Handle and store under inert gas. Air sensitive.

Chemical Identifiers

CAS 51-45-6
Molecular Formula C5H9N3
Molecular Weight (g/mol) 111.15
MDL Number MFCD00005210,MFCD00128939
InChI Key NTYJJOPFIAHURM-UHFFFAOYSA-N
Synonym histamine, 1h-imidazole-4-ethanamine, 2-4-imidazolyl ethylamine, ergotidine, 2-1h-imidazol-5-yl ethanamine, ergamine, eramin, 5-imidazoleethylamine, theramine, free histamine
PubChem CID 774
ChEBI CHEBI:18295
SMILES NCCC1=CN=CN1

Specifications

Color White
Quantity 1 g
UN Number UN2811
Beilstein 2012
Merck Index 14,4719
Solubility Information Soluble in water,alcohol,and hot chloroform.
IUPAC Name 2-(1H-imidazol-5-yl)ethanamine
Formula Weight 111.15
Physical Form Powder
Chemical Name or Material Histamine

Safety and Handling

Hazard Category H301-H315-H317-H319-H334-H335
Hazard Statement GHS H Statement
H301-H334-H315-H319-H317-H335
Toxic if swallowed.
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Causes skin irritation.
Causes serious eye irritation.
May cause an allergic skin reaction.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P270-P271-P272-P280-P285-P301+P310-P302+P352-P304+P340-P305+P351+P338-P330-P333+P313-P342+P311-P362-P501c
DOTInformation Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber 200-100-6
RTECSNumber MS1050000
TSCA Yes
Recommended Storage Keep cold

RUO – Research Use Only