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Histamine dihydrochloride, 98+%
CAS: 56-92-8 | C5H11Cl2N3 | 184.06 g/mol
Supplier: Thermo Scientific Chemicals L0919806
Description
Histamine dihydrochloride has been shown to activate nitric oxide synthetase and suppress or inhibit the generation of reactive oxygen species (ROS). Inhibition of ROS by histamine dihydrochloride allows activation of T cells and NK cells by IL-2. In a rat model, histamine dihydrochloride suppressed ROS generated by Kupffer cells through the H2 histamine receptor. It is a potent vasodilator and endogenous histamine receptor agonist.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsHistamine dihydrochloride has been shown to activate nitric oxide synthetase and suppress or inhibit the generation of reactive oxygen species (ROS). Inhibition of ROS by histamine dihydrochloride allows activation of T cells and NK cells by IL-2. In a rat model, histamine dihydrochloride suppressed ROS generated by Kupffer cells through the H2 histamine receptor. It is a potent vasodilator and endogenous histamine receptor agonist.
Solubility
Very soluble in water and methanol. Soluble in ethanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents. Store away from oxidizing agents. Store at 4°C.
Specifications
| Histamine dihydrochloride | |
| 245°C to 249°C | |
| MFCD00012703 | |
| 3624116 | |
| histamine dihydrochloride, histamine 2hcl, 2-1h-imidazol-4-yl ethanamine dihydrochloride, 1h-imidazole-4-ethanamine dihydrochloride, 1h-imidazole-4-ethanamine, dihydrochloride, peremin, ceplene, 2-1h-imidazol-4-yl ethylamine dihydrochloride, 2-4-imidazolyl ethylamine dihydrochloride, histaminedium dichloride | |
| PPZMYIBUHIPZOS-UHFFFAOYSA-N | |
| 2-(1H-imidazol-5-yl)ethanamine;dihydrochloride | |
| 5818 | |
| ≥98% |
| 56-92-8 | |
| C5H11Cl2N3 | |
| 5 g | |
| 14,4719 | |
| Very soluble in water and methanol. Soluble in ethanol. | |
| [H+].[H+].[Cl-].[Cl-].NCCC1=CN=CN1 | |
| 184.06 | |
| 184.07 |
Chemical Identifiers
| 56-92-8 | |
| 184.06 | |
| PPZMYIBUHIPZOS-UHFFFAOYSA-N | |
| 5818 | |
| [H+].[H+].[Cl-].[Cl-].NCCC1=CN=CN1 |
| C5H11Cl2N3 | |
| MFCD00012703 | |
| histamine dihydrochloride, histamine 2hcl, 2-1h-imidazol-4-yl ethanamine dihydrochloride, 1h-imidazole-4-ethanamine dihydrochloride, 1h-imidazole-4-ethanamine, dihydrochloride, peremin, ceplene, 2-1h-imidazol-4-yl ethylamine dihydrochloride, 2-4-imidazolyl ethylamine dihydrochloride, histaminedium dichloride | |
| 2-(1H-imidazol-5-yl)ethanamine;dihydrochloride |
Safety and Handling
GHS H Statement
H334-H335-H315-H319-H317
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause respiratory irritation.
Causes skin irritation.
Causes serious eye irritation.
May cause an allergic skin reaction.
P261-P264b-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P333+P313-P342+P311-P362-P501c
H315-H317-H319-H334-H335
EINECSNumber : 200-298-4
RTECSNumber : MS1575000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only