Penicillin was originally purified from fungi Penicillium that acts by interfering directly with turnover of bacterial cell wall and indirectly by triggering release of enzymes that alter the cell wall. Streptomycin was originally purified from Streptomyces griseus. It acts by binding to 30S subunit of bacterial ribosome, leading to inhibition of protein synthesis and death in susceptible bacteria.
- Contains 10,000 units/mL of penicillin
- 10,000μg/mL of streptomycin in a 10 mM citrate buffer (for pH stability)