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Fluorescein disodium salt
Fluorescein disodium salt (uranin, fluorescite, acid yellow 73, CAS # 518-45-6) is the salt of the xanthene dye commonly used for fluorescent tracing. | CAS: 518-47-8 | C20H10Na2O5 | 376.28 g/mol
$70.08 - $159.04
Chemical Identifiers
| CAS | 518-47-8 |
|---|---|
| Molecular Formula | C20H10Na2O5 |
| Molecular Weight (g/mol) | 376.28 |
| MDL Number | MFCD00167039 |
| InChI Key | NJDNXYGOVLYJHP-UHFFFAOYSA-L |
| Synonym | Acid Yellow 73; C.I. 45350 |
| IUPAC Name | disodium 2-(6-oxido-3-oxo-3H-xanthen-9-yl)benzoate |
| SMILES | [Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C1=C2C=CC(=O)C=C2OC2=CC([O-])=CC=C12 |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ6154922
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Thermo Scientific Chemicals
J6154922 |
100 g |
Each for $70.08
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AAJ6154936
|
Thermo Scientific Chemicals
J6154936 |
500 g |
Each for $159.04
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Description
Fluorescein disodium salt is used as fluorescent tracer, has been utilized in studies as a drug model, as a penetrating dye . Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius.1 Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models. The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes.5 Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP). Additional reported uses include microscopy, as a gain medium in dye laser use and to detect latent blood stains in vitro. Common derivatives of Fluorescein include fluorescein isothiocyanate (FITC), eosin and Rose Bengal (sc-296278) and Rose Bengal sodium salt
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Fluorescein disodium salt is a yellow-green phthalate indicator dye that is pH-sensitive
• It has a maximum absorbance of 494nm and maximum emission of 521nm
Application
• Fluorescein disodium salt can be used as a fluorescent protein labeler
• Fluorescein is also useful for the staining of cells and organelles
Chemical Identifiers
| 518-47-8 | |
| 376.28 | |
| NJDNXYGOVLYJHP-UHFFFAOYSA-L | |
| disodium 2-(6-oxido-3-oxo-3H-xanthen-9-yl)benzoate |
| C20H10Na2O5 | |
| MFCD00167039 | |
| Acid Yellow 73; C.I. 45350 | |
| [Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C1=C2C=CC(=O)C=C2OC2=CC([O-])=CC=C12 |
Specifications
| 518-47-8 | |
| C20H10Na2O5 | |
| 100 g | |
| 14,4159 | |
| Soluble in water at 1mg/ml | |
| [Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C1=C2C=CC(=O)C=C2OC2=CC([O-])=CC=C12 | |
| 376.28 | |
| Powder |
| Brown-Red | |
| MFCD00167039 | |
| 3833041 | |
| Acid Yellow 73; C.I. 45350 | |
| NJDNXYGOVLYJHP-UHFFFAOYSA-L | |
| disodium 2-(6-oxido-3-oxo-3H-xanthen-9-yl)benzoate | |
| 376.28 | |
| Fluorescein disodium salt |
Safety and Handling
EINECSNumber : 208-253-0
RTECSNumber : LM5425000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only