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Thermo Scientific™ Finasteride, 98%
Finasteride, CAS # 98319-26-7, is a 5α-reductase inhibitor that blocks conversion of testosterone and inhibits neurosteroid production.
Chemical Identifiers
| CAS | 98319-26-7 |
|---|---|
| Molecular Formula | C23H36N2O2 |
| Molecular Weight (g/mol) | 372.54 |
| InChI Key | DBEPLOCGEIEOCV-WSBQPABSSA-N |
| Synonym | finasteride, proscar, propecia, finastid, prostide, chibro-proscar, finasterida, finasteridum, finpecia, finasteridum inn-latin |
| PubChem CID | 57363 |
| ChEBI | CHEBI:5062 |
| IUPAC Name | (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide |
| SMILES | CC12CCC3C(C1CCC2C(=O)NC(C)(C)C)CCC4C3(C=CC(=O)N4)C |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|
AC458000010
|
Thermo Scientific™
458000010 |
1g |
N/A
|
N/A | |||||
| Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance. | |||||||||
|
AC458000050
|
Thermo Scientific™
458000050 |
5g |
N/A
|
N/A | |||||
| Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance. | |||||||||
Description
This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
• Finasteride is an inhibitor of the enzyme 5α-reductase, which converts testosterone to dihydrotestosterone (DHT)
• Finasteride also has been explored in neuroscience, as 5α-reductase enzymes are present in the central nervous system
• Finasteride has been seen to cross the blood-brain barrier and block production of neurosteroids
Applications
• Finasteride is mainly used in studies of prostate hyperplasia and tumors in mice, and can be studied in vitro or in vivo for its effects on hyperplasia, proliferation, and antioxidant activity
• Its activity has also been explored in brain, liver and testis tissues
• In vivo injection of finasteride has been shown to decrease neurogenesis and influence neuronal plasticity in mice
Chemical Identifiers
| 98319-26-7 | |
| 372.54 | |
| finasteride, proscar, propecia, finastid, prostide, chibro-proscar, finasterida, finasteridum, finpecia, finasteridum inn-latin | |
| CHEBI:5062 | |
| CC12CCC3C(C1CCC2C(=O)NC(C)(C)C)CCC4C3(C=CC(=O)N4)C |
| C23H36N2O2 | |
| DBEPLOCGEIEOCV-WSBQPABSSA-N | |
| 57363 | |
| (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide |
Specifications
| 98319-26-7 | |
| 97.5% min. (HPLC) | |
| C23H36N2O2 | |
| finasteride, proscar, propecia, finastid, prostide, chibro-proscar, finasterida, finasteridum, finpecia, finasteridum inn-latin | |
| DBEPLOCGEIEOCV-WSBQPABSSA-N | |
| (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide | |
| 57363 | |
| 372.54 | |
| Finasteride |
| Authentic | |
| Glass Bottle | |
| 1g | |
| Solubility in water: very slightly soluble. | |
| CC12CCC3C(C1CCC2C(=O)NC(C)(C)C)CCC4C3(C=CC(=O)N4)C | |
| 372.54 | |
| CHEBI:5062 | |
| 98% |
Safety and Handling
GHS H Statement
Harmful if swallowed.
May damage the unborn child.
GHS P Statement
Wash face,hands and any exposed skin thoroughly after handling.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Obtain special instructions before use.
Use personal protective equipment as
GHS Signal Word: Danger
RUO â Research Use Only