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  6. Thermo Scientific Chemicals Finastéride, 98%

Thermo Scientific Chemicals Finastéride, 98%

Numéro de catalogue. AC458000010
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AC458000010 1 g
AC458000050 5 g
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Numéro de catalogue. AC458000010 Fournisseur Thermo Scientific Chemicals Code fournisseur 458000010

Description

La finastéride, CAS # 98319-26-7, est un inhibiteur de la 5-réductase α qui bloque la conversion de la testostérone et inhibe la production de neurostéroïdes.

Ce Thermo Scientific Chemicals produit de marque faisait à l’origine partie du portefeuille de produits d’Acros Organics. Certains documents et informations d’étiquetage peuvent faire référence à l’ancienne marque. Le code produit / article original d’Acros Organics ou la référence SKU n’a pas changé dans le cadre de la transition de la marque vers Thermo Scientific Chemicals.

General Description

  • Finasteride is an inhibitor of the enzyme 5α-reductase, which converts testosterone to dihydrotestosterone (DHT)
  • Finasteride also has been explored in neuroscience, as 5α-reductase enzymes are present in the central nervous system
  • Finasteride has been seen to cross the blood-brain barrier and block production of neurosteroids

Applications

  • Finasteride is mainly used in studies of prostate hyperplasia and tumors in mice, and can be studied in vitro or in vivo for its effects on hyperplasia, proliferation, and antioxidant activity
  • Its activity has also been explored in brain, liver and testis tissues
  • In vivo injection of finasteride has been shown to decrease neurogenesis and influence neuronal plasticity in mice

Identifiants chimiques

CAS 98319-26-7
Formule moléculaire C23H36N2O2
Poids moléculaire (g/mol) 372.54
Clé InChI DBEPLOCGEIEOCV-WSBQPABSSA-N
Synonyme finasteride, proscar, propecia, finastid, prostide, chibro-proscar, finasterida, finasteridum, finpecia, finasteridum inn-latin
PubChem CID 57363
ChEBI CHEBI:5062
Nom de l’IUPAC (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
SOURIRES CC12CCC3C(C1CCC2C(=O)NC(C)(C)C)CCC4C3(C=CC(=O)N4)C

Spécifications

Nom ou substance chimique Finasteride
Point de fusion 252.0°C to 254.0°C
Spectre infrarouge Authentic
Fourchette de pourcentages d’essai 97.5% min. (HPLC)
Emballage Glass Bottle
Quantité 1 g
Renseignements sur la solubilité Solubility in water: very slightly soluble.
Poids de formule 372.54
Pourcentage de pureté 98%

Sécurité et manipulation

Hazard Category GHS Signal Word: Danger
Hazard Statement GHS H Statement
Harmful if swallowed.
May damage the unborn child.
Precautionary Statement GHS P Statement
Wash face,hands and any exposed skin thoroughly after handling.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Obtain special instructions before use.
Use personal protective equipment as

Utilisation uniquement de la recherche RUO –