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(-)-Epigallocatechin Gallate, MP Biomedicals™
Inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate, MP Biomedicals is a polyphenolic, tumor-inhibiting constituent of green tea. ECGC is an antioxidant polyphenol flavonoid that inhibits cellular oxidation of low density lipoprote
$148.19 - $148.19
Chemical Identifiers
| CAS | 989-51-5 |
|---|---|
| Molecular Formula | C22H18O11 |
| Molecular Weight (g/mol) | 458.375 |
| InChI Key | WMBWREPUVVBILR-WIYYLYMNSA-N |
| Synonym | =--epigallocatechin gallate, egcg, epigallocatechin gallate, epigallocatechin 3-gallate, tea catechin, epigallocatechin-3-gallate, =--epigallocatechin-3-o-gallate, teavigo, =--epigallocatechol gallate, epigallocatechin-3-monogallate |
| PubChem CID | 65064 |
| ChEBI | CHEBI:4806 |
| IUPAC Name | [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate |
| SMILES | C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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MP219916550
|
MP Biomedicals Inc
0219916550 |
50 mg |
Each for $148.19
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Description
A natural component of green tea with a variety of biological functions:
- Bocks the activation of EGF receptors and HER-2 receptors
- Inhibits fatty acid synthase and glutamate dehydrogenase activity
- Inhibits the peroxynitrite-induced formation of the oxidative injury markers 8-hydroxy-2-deoxy guanosine and 3-nitrotyrosine, apoptosis in human prostate cancer cells
- Selectively inhibits activation of JNK/SAPK signaling pathway and suppresses proliferation of vascular smooth muscle cells
- Shows growth inhibitory effects on tumor cells but not their normal counterparts
- Inhibits telomerase, a fast-binding and reversible fatty acid synthase inhibitor
- Inhibits PMA-induced skin thickening
- Inhibits activation of interleukin-1a mRNA and protein expression
- Inhibits nitric oxide synthase (iNOS) gene expression
- At μM concentrations, inhibits VEGF-induced tyrosine phosphorylation
Chemical Identifiers
| 989-51-5 | |
| 458.375 | |
| =--epigallocatechin gallate, egcg, epigallocatechin gallate, epigallocatechin 3-gallate, tea catechin, epigallocatechin-3-gallate, =--epigallocatechin-3-o-gallate, teavigo, =--epigallocatechol gallate, epigallocatechin-3-monogallate | |
| CHEBI:4806 | |
| C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O |
| C22H18O11 | |
| WMBWREPUVVBILR-WIYYLYMNSA-N | |
| 65064 | |
| [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate |
Specifications
| 989-51-5 | |
| C22H18O11 | |
| =--epigallocatechin gallate, egcg, epigallocatechin gallate, epigallocatechin 3-gallate, tea catechin, epigallocatechin-3-gallate, =--epigallocatechin-3-o-gallate, teavigo, =--epigallocatechol gallate, epigallocatechin-3-monogallate | |
| WMBWREPUVVBILR-WIYYLYMNSA-N | |
| C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O | |
| 458.375 | |
| CHEBI:4806 | |
| ≥95% |
| 218°C (literature) | |
| 50 mg | |
| Soluble in water (5mg/mL, clear, faint pink colored solution). | |
| −185° ± 2° (ethanol) (Lit.) | |
| [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate | |
| 65064 | |
| 458.4g/mol | |
| Powder |
Safety and Handling
Recommended Storage : Store at 4°C.