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Doxycycline hydrochloride
Doxycycline hydrochloride, CAS # 10592-13-9, is the hydrochloride salt form of doxycycline that shows antibacterial and antimalarial activities. | CAS: 10592-13-9 | C22H25ClN2O8 | 480.90 g/mol
$193.25 - $755.58
Chemical Identifiers
| CAS | 10592-13-9 |
|---|---|
| Molecular Formula | C22H25ClN2O8 |
| Molecular Weight (g/mol) | 480.90 |
| MDL Number | MFCD03427564 |
| InChI Key | VLUQVUWDECWBTL-UQVCFKGQSA-N |
| PubChem CID | 54706018 |
| IUPAC Name | (1S,3Z,4aS,11R,11aR,12S,12aR)-3-[amino(hydroxy)methylidene]-4a,6,7,12-tetrahydroxy-N,N,11-trimethyl-2,4,5-trioxo-1,2,3,4,4a,5,11,11a,12,12a-decahydrotetracen-1-aminium chloride |
| SMILES | [Cl-].C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H]([NH+](C)C)C(=O)\C(=C(/N)O)C(=O)[C@@]3(O)C(=O)C2=C(O)C2=C(O)C=CC=C12 |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ6042206
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Thermo Scientific Chemicals
J6042206 |
5 g |
Each for $193.25
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AAJ6042214
|
Thermo Scientific Chemicals
J6042214 |
25 g |
Each for $755.58
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Description
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Suitable for battery materials development.
General Description
- Doxycycline hydrochloride is a compound that shows antibacterial and antimicrobial activities against several species, including Pseudomonas aeruginosa, Plasmodium falciparum, and Escherichia coli. It is also a bacteriostatic
- It can block the binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis
Application
- It is used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and eliminate Ixodes scapularis ticks
- Doxycycline hydrochloride is also considered to be a broad-spectrum inhibitor used to inhibit matrix metalloproteinases (MMP), such as type 1 collagenase, in wound healing and tissue remodeling studies. Due to this activity, it can inhibit angiogenesis and reduce lung metastases
Chemical Identifiers
| 10592-13-9 | |
| 480.90 | |
| VLUQVUWDECWBTL-UQVCFKGQSA-N | |
| (1S,3Z,4aS,11R,11aR,12S,12aR)-3-[amino(hydroxy)methylidene]-4a,6,7,12-tetrahydroxy-N,N,11-trimethyl-2,4,5-trioxo-1,2,3,4,4a,5,11,11a,12,12a-decahydrotetracen-1-aminium chloride |
| C22H25ClN2O8 | |
| MFCD03427564 | |
| 54706018 | |
| [Cl-].C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H]([NH+](C)C)C(=O)\C(=C(/N)O)C(=O)[C@@]3(O)C(=O)C2=C(O)C2=C(O)C=CC=C12 |
Specifications
| Doxycycline Hydrochloride | |
| 10592-13-9 | |
| Yellow | |
| C22H25ClN2O8 | |
| Soluble in water to 50mg/ml; May require warming. | |
| [Cl-].C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H]([NH+](C)C)C(=O)\C(=C(/N)O)C(=O)[C@@]3(O)C(=O)C2=C(O)C2=C(O)C=CC=C12 | |
| 480.90 | |
| 480.9 |
| Crystalline Powder | |
| 195°C to 201°C | |
| 5 g | |
| MFCD03427564 | |
| VLUQVUWDECWBTL-UQVCFKGQSA-N | |
| (1S,3Z,4aS,11R,11aR,12S,12aR)-3-[amino(hydroxy)methylidene]-4a,6,7,12-tetrahydroxy-N,N,11-trimethyl-2,4,5-trioxo-1,2,3,4,4a,5,11,11a,12,12a-decahydrotetracen-1-aminium chloride | |
| 54706018 | |
| Doxycycline hydrochloride |
Safety and Handling
GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302+H312+H332-H315-H319-H335
EINECSNumber : 234-198-7
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only