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Diethyl dicarbonate, 97%
Description
Ribonuclease inhibitorDiethyl dicarbonate acts as an inhibitor of ryanodine binding to ryanodine/calcium(II) receptor channel. It is useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Further, it inhibits platelet-activating factor acetyl hydrolase. In addition to this, it is involved in the modification reagent for His and Tyr residues in proteins.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Ribonuclease inhibitorDiethyl dicarbonate acts as an inhibitor of ryanodine binding to ryanodine/calcium(II) receptor channel. It is useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Further, it inhibits platelet-activating factor acetyl hydrolase. In addition to this, it is involved in the modification reagent for His and Tyr residues in proteins.
Solubility
Miscible with chloroform, ethanol, esters, ketones and hydrocarbons. Slightly miscible with water.
Notes
Store in cool place. Incompatible with strong oxidizing agents, strong reducing agents, strong acids, strong bases and ammonia.
Ribonuclease inhibitorDiethyl dicarbonate acts as an inhibitor of ryanodine binding to ryanodine/calcium(II) receptor channel. It is useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Further, it inhibits platelet-activating factor acetyl hydrolase. In addition to this, it is involved in the modification reagent for His and Tyr residues in proteins.
Solubility
Miscible with chloroform, ethanol, esters, ketones and hydrocarbons. Slightly miscible with water.
Notes
Store in cool place. Incompatible with strong oxidizing agents, strong reducing agents, strong acids, strong bases and ammonia.
Specifications
Specifications
| Density | 1.101 |
| Boiling Point | 93°C to 94°C (18 mmHg) |
| Flash Point | 69°C (156°F) |
| Assay Percent Range | 0.97 |
| Refractive Index | 1.398 |
| Quantity | 5 g |
| Beilstein | 637031 |
| Sensitivity | Moisture sensitive |
| Merck Index | 14,7998 |
| Solubility Information | Miscible with chloroform,ethanol,esters,ketones and hydrocarbons. Slightly miscible with water. |
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Safety and Handling
| Hazard Category | H227-H302-H315-H319-H332-H335 |
| Hazard Statement | GHS H Statement H302-H315-H319-H335-H227 Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid. |
| Precautionary Statement | P210-P235-P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P370+P378q-P501c |
| EINECSNumber | 216-542-8 |
| RTECSNumber | LQ9350000 |
| TSCA | Yes |
| storageNote1 | Moisture Sensitive |
| Recommended Storage | Keep cold; Store under Nitrogen |
RUO – Research Use Only