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Diethyl (bromodifluoromethyl)phosphonate, 97%
CAS: 65094-22-6 | C5H10BrF2O3P | 267.01 g/mol
$59.14 - $559.60
Chemical Identifiers
| CAS | 65094-22-6 |
|---|---|
| Molecular Formula | C5H10BrF2O3P |
| Molecular Weight (g/mol) | 267.01 |
| MDL Number | MFCD00069118 |
| InChI Key | QRADKVYIJIAENZ-UHFFFAOYSA-N |
| Synonym | diethyl bromodifluoromethyl phosphonate, bromodifluoromethyl diethylphosphonate, diethyl bromodifluoromethanephosphonate, diethyl bromodifluoromethylphosphonate, bromodifluoromethyl phosphonic acid diethyl ester, 1-bromo difluoro methyl-ethoxyphosphoryl oxyethane, phosphonic acid, bromodifluoromethyl-, diethyl ester, pubchem24183, acmc-20ai7p |
| PubChem CID | 144101 |
| IUPAC Name | 1-[[bromo(difluoro)methyl]-ethoxyphosphoryl]oxyethane |
| SMILES | CCOP(=O)(OCC)C(F)(F)Br |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAL1671503
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Thermo Scientific Chemicals
L1671503 |
1 g |
Each for $59.14
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AAL1671506
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Thermo Scientific Chemicals
L1671506 |
5 g |
Each for $159.59
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AAL1671514
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Thermo Scientific Chemicals
L1671514 |
25 g |
Each for $559.60
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Description
Diethyl (bromodifluoromethyl)phosphonate is used as a reactant for the preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3), synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps and P-C bond cleavage on basic hydrolysis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsDiethyl (bromodifluoromethyl)phosphonate is used as a reactant for the preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3), synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps and P-C bond cleavage on basic hydrolysis.
Solubility
Not miscible or difficult to mix in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Incompatible with oxidizing agents.
Chemical Identifiers
| 65094-22-6 | |
| 267.01 | |
| QRADKVYIJIAENZ-UHFFFAOYSA-N | |
| 144101 | |
| CCOP(=O)(OCC)C(F)(F)Br |
| C5H10BrF2O3P | |
| MFCD00069118 | |
| diethyl bromodifluoromethyl phosphonate, bromodifluoromethyl diethylphosphonate, diethyl bromodifluoromethanephosphonate, diethyl bromodifluoromethylphosphonate, bromodifluoromethyl phosphonic acid diethyl ester, 1-bromo difluoro methyl-ethoxyphosphoryl oxyethane, phosphonic acid, bromodifluoromethyl-, diethyl ester, pubchem24183, acmc-20ai7p | |
| 1-[[bromo(difluoro)methyl]-ethoxyphosphoryl]oxyethane |
Specifications
| 65094-22-6 | |
| 99°C to 102°C (16 mmHg) | |
| C5H10BrF2O3P | |
| MFCD00069118 | |
| 1944045 | |
| Not miscible or difficult to mix in water. | |
| CCOP(=O)(OCC)C(F)(F)Br | |
| 267.01 | |
| 267.01 | |
| Diethyl (bromodifluoromethyl)phosphonate |
| 1.503 | |
| >110°C (230°F) | |
| 1.416 | |
| 1 g | |
| diethyl bromodifluoromethyl phosphonate, bromodifluoromethyl diethylphosphonate, diethyl bromodifluoromethanephosphonate, diethyl bromodifluoromethylphosphonate, bromodifluoromethyl phosphonic acid diethyl ester, 1-bromo difluoro methyl-ethoxyphosphoryl oxyethane, phosphonic acid, bromodifluoromethyl-, diethyl ester, pubchem24183, acmc-20ai7p | |
| QRADKVYIJIAENZ-UHFFFAOYSA-N | |
| 1-[[bromo(difluoro)methyl]-ethoxyphosphoryl]oxyethane | |
| 144101 | |
| 97% |
Safety and Handling
GHS H Statement
H315-H319
Causes skin irritation.
Causes serious eye irritation.
P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362
H315-H319
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only