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Di-tert-butyl N,N-diethylphosphoramidite, 94%

CAS: 117924-33-1 | C12H28NO2P | 249.335 g/mol

$511.95 - $511.95

Chemical Identifiers

CAS 117924-33-1
Molecular Formula C12H28NO2P
Molecular Weight (g/mol) 249.335
MDL Number MFCD00134307
InChI Key KUKSUQKELVOKBH-UHFFFAOYSA-N
Synonym di-tert-butyl n,n-diethylphosphoramidite, di-tert-butyl diethylphosphoramidite, di-t-butyl n,n-diethylphosphoramidite, phosphoramidous acid, diethyl-, bis 1,1-dimethylethyl ester, n-bis 2-methylpropan-2-yl oxy phosphanyl-n-ethylethanamine, acmc-1c42i, di-t-butyl diethylphosphoramidite, di-tert-butyl diethylamidophosphite, di-tert-butoxy diethylamino phosphine
PubChem CID 4251849
IUPAC Name N-[bis[(2-methylpropan-2-yl)oxy]phosphanyl]-N-ethylethanamine
SMILES CCN(CC)P(OC(C)(C)C)OC(C)(C)C
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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAH2738006
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Thermo Scientific Chemicals
H2738006
5 g
Each for $511.95
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Description

Description

A useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters. It is applied as a phosphitylating agent in water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, a2a-selective adenosine receptor antagonists.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
A useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters. It is applied as a phosphitylating agent in water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, a2a-selective adenosine receptor antagonists.

Solubility
Hydrolyzes in water. Soluble in chloroform and methanol.

Notes
Moisture sensitive. Store away from water/moisture, heat and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Keep it refrigerated. Keep ignition sources away.
Specifications

Chemical Identifiers

117924-33-1
249.335
KUKSUQKELVOKBH-UHFFFAOYSA-N
4251849
CCN(CC)P(OC(C)(C)C)OC(C)(C)C
C12H28NO2P
MFCD00134307
di-tert-butyl n,n-diethylphosphoramidite, di-tert-butyl diethylphosphoramidite, di-t-butyl n,n-diethylphosphoramidite, phosphoramidous acid, diethyl-, bis 1,1-dimethylethyl ester, n-bis 2-methylpropan-2-yl oxy phosphanyl-n-ethylethanamine, acmc-1c42i, di-t-butyl diethylphosphoramidite, di-tert-butyl diethylamidophosphite, di-tert-butoxy diethylamino phosphine
N-[bis[(2-methylpropan-2-yl)oxy]phosphanyl]-N-ethylethanamine

Specifications

117924-33-1
39°C to 41°C (0.3 mmHg)
C12H28NO2P
MFCD00134307
Moisture sensitive; May form a precipitate
Hydrolyzes in water. Soluble in chloroform and methanol.
CCN(CC)P(OC(C)(C)C)OC(C)(C)C
249.335
249.33
Di-tert-butyl N,N-diethylphosphoramidite
0.896
78°C (172°F)
1.434
5 g
di-tert-butyl n,n-diethylphosphoramidite, di-tert-butyl diethylphosphoramidite, di-t-butyl n,n-diethylphosphoramidite, phosphoramidous acid, diethyl-, bis 1,1-dimethylethyl ester, n-bis 2-methylpropan-2-yl oxy phosphanyl-n-ethylethanamine, acmc-1c42i, di-t-butyl diethylphosphoramidite, di-tert-butyl diethylamidophosphite, di-tert-butoxy diethylamino phosphine
KUKSUQKELVOKBH-UHFFFAOYSA-N
N-[bis[(2-methylpropan-2-yl)oxy]phosphanyl]-N-ethylethanamine
4251849
94%
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Safety and Handling

Safety and Handling

GHS H Statement
H315-H319-H227
Causes skin irritation.
Causes serious eye irritation.
Combustible liquid.

P210-P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362-P370+P378q-P501c

H227-H315-H319

TSCA : No

Recommended Storage : Keep cold

SDS
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RUO – Research Use Only