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Dextran Sulfate Sodium Salt, Colitis Grade (36,000 to 50,000), MP Biomedicals™

Induces severe colitis (inflammatory bowel disease) in laboratory animals

Supplier:  MP Biomedicals Inc 0216011025

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Catalog No. MP216011025



Description

Description

Induces severe colitis (inflammatory bowel disease) in laboratory animals

Dextran sulfate sodium salt, or DSS, is a synthetic sulfated branched polysaccharide derivative of dextran that has multiple uses in biomedical and clinical research. One important property of DSS is to trigger colitis in mice and rats when administered in drinking water. DSS binds to medium-chain-length fatty acids in the colon and induces intestinal inflammation. Colitis-grade DSS (MW = 36,000 to 50,000) from MP Bio is one of the most widely used products based on peer reviewed scientific publications.

  • Induces severe colitis (inflammatory bowel disease)
  • Highest sulfur content – 19%
  • Highest chirality - +104° of specific rotation
  • Lowest pH – 6.2 at 1% solution
Specifications

Specifications

White
5 to 7.11 (1% aqueous solution)
9011-18-1
92°C
MFCD00081551
25 g
*-OC[C@H]1O[C@H](OC[C@H]2O[C@H](-*)[C@H](O[*])[C@@H](O[*])[C@@H]2O[*])[C@H](O[*])[C@@H](O-*)[C@@H]1O[*]
40,000
Colitis Grade
Plastic Container
Dextran Sulfate Sodium Salt
Powder
310°C
(C6H7O5)m(C6H7O5)n
Soluble in water
BLFLLBZGZJTVJG-UHFFFAOYSA-N
Dextran sulfate sodium salt
Used for inducing ulcerative colitis in animals and extensively to study colon cancer developing in relation to colonic inflammation
<10%
SDS
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Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.