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Deoxycholic acid, 99%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals B2006136
Description
Deoxycholic acid has been used in a modified procedure to recover 40-80% of a protein from a 1 μg/mL solution. It forms complexes with fatty acid. Used as an emulsifying agent in food, a precursor in the synthesis of cortisone, and a gallbladder stimulant. It has been used to study assess how physiological concentrations of ursodeoxycholic acid (UDCA) vs. deoxycholic acid (DCA) affect barrier function in mouse intestinal tissue. Deoxycholic acid has been used in a study to assess a pH-Responsive Mechanism of a Deoxycholic Acid and Folate Co-Modified Chitosan Micelle under Cancerous Environment. It has also been used in a study to investigate dose-dependent anti-inflammatory effect of ursodeoxycholic acid in experimental colitis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsDeoxycholic acid has been used in a modified procedure to recover 40-80% of a protein from a 1 µg/mL solution. It forms complexes with fatty acid. Used as an emulsifying agent in food, a precursor in the synthesis of cortisone, and a gallbladder stimulant. It has been used to study assess how physiological concentrations of ursodeoxycholic acid (UDCA) vs. deoxycholic acid (DCA) affect barrier function in mouse intestinal tissue. Deoxycholic acid has been used in a study to assess a pH-Responsive Mechanism of a Deoxycholic Acid and Folate Co-Modified Chitosan Micelle under Cancerous Environment. It has also been used in a study to investigate dose-dependent anti-inflammatory effect of ursodeoxycholic acid in experimental colitis.
Solubility
The free acid is soluble at 0.044 g/L in water at 20°C. Solubility in methanol is almost transparent.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Specifications
| Deoxycholic acid | |
| 172°C to 176°C | |
| MFCD00003673 | |
| 3219882 | |
| deoxycholic acid, deoxycholate, desoxycholic acid, choleic acid, cholerebic, cholorebic, degalol, deoxycholatic acid, droxolan, pyrochol | |
| KXGVEGMKQFWNSR-LLQZFEROSA-N | |
| [H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C | |
| 392.58 | |
| CHEBI:28834 | |
| 99% |
| 83-44-3 | |
| C24H40O4 | |
| 500 g | |
| 14,2899 | |
| The free acid is soluble at 0.044g/L in water at 20°C. Solubility in methanol is almost transparent. | |
| +54° (c=2 in Ethanol) | |
| (4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid | |
| 222528 | |
| 392.58 |
Chemical Identifiers
| 83-44-3 | |
| 392.58 | |
| KXGVEGMKQFWNSR-LLQZFEROSA-N | |
| 222528 | |
| (4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid |
| C24H40O4 | |
| MFCD00003673 | |
| deoxycholic acid, deoxycholate, desoxycholic acid, choleic acid, cholerebic, cholorebic, degalol, deoxycholatic acid, droxolan, pyrochol | |
| CHEBI:28834 | |
| [H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C |
Safety and Handling
GHS H Statement
H301
Toxic if swallowed.
P264b-P270-P301+P312-P330-P501c
H302
EINECSNumber : 201-478-5
RTECSNumber : FZ2100000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only