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Gibco™ CTS™ Detachable Dynabeads™ CD4

Numéro de catalogue. A56994
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15 mL vial
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Numéro de catalogue. Quantity
A56994 15 mL vial
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Numéro de catalogue. A56994 Fournisseur Gibco™ Code fournisseur A56994
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Description

CTS Detachable Dynabeads CD4 for positive isolation of CD4+ T cells and active release of Dynabeads post-isolation.

Gibco CTS Detachable Dynabeads CD4 are intended for ex vivo isolation of CD4+ T cell subsets. Combined with CTS Detachable Dynabeads Release Buffer (Cat. No. A5588301, A5588302, or A5588303), it is a first-of-its-kind cGMP cell selection technology with an active release mechanism for process development, clinical trial, and commercial manufacturing use. This product is also commonly used with CTS Detachable Dynabeads CD8 (Cat. No. A56995).

Features of CTS Detachable Dynabeads CD4 include:

  • Empower users with process flexibility by allowing active release of beads from target cells at any time
  • Optimize target cell purity and yield thanks to the active release mechanism that gives users more control
  • Provide an automation-friendly solution by working directly with the CTS DynaCellect Magnetic Separation System
  • Enable consistent performance in light of biological variability within the starting material
  • Suitable for both autologous and allogeneic cell therapy manufacturing processes

These Detachable Dynabeads are intended for use with CTS Detachable Dynabeads Release Buffer, which has an active ingredient, biotin, that competitively displaces a biotin derivative on the surface of the beads. This proprietary mechanism allows users to achieve active release of the beads from target cells at any time within their process.

Based on a recommended 4-to-1 bead-to-target-cell ratio (not total nucleated cell number), one 15 mL vial can theoretically isolate up to 1.5 x 109 CD4+ T cells.

CTS Detachable Dynabeads also include a Drug Master File (DMF) to support cross-referencing in regulatory submissions prior to clinical trial and commercial manufacturing use.

Spécifications

Concentration 4 x 108 beads/mL
Content And Storage CTS™ Detachable Dynabeads™ CD4, 15 mL.

Store at 2°C to 8°C with vial upright to keep beads in suspension.
Color Brown
Material Polystyrene
Product Type Cell Isolation Reagent
For Use With (Equipment) CTS™ DynaCellect™ Magnetic Separation System
Product Line CTS Detachable Dynabeads
Purity or Quality Grade GMP-grade
Quantity 15 mL vial
Shipping Condition Ships at 2°C to 8°C with wet (not frozen) gel packs. Vial must remain upright to keep beads in suspension.
Volume (Metric) 15 mL
Diameter (Metric) 4.5 μm
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For Research Use or Manufacturing of Cell, Gene, or Tissue-Based Products. CAUTION: Not intended for direct administration into humans or animals.