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Gibco™ Collagen I, rat tail 
Collagen I Rat Protein, Tail
Supplier: Gibco™ A1048301
Description
Collagen I, Rat Tail is the most common fibrillar collagen (90%) found in skin, bone, tendons, and other connective tissues. It is supplied at ~4 mg/mL in 20 mM acetic acid, providing the flexibility to dilute to lower concentrations. (See Certificate of Analysis for exact concentration.) The detailed gelling procedure forms a firm, clear gel for 3D applications.
Collagen is a fibrous protein that consists of three α-chains that can combine to form a rope-like triple helix, providing tensile strength to the extracellular matrix (ECM) where it plays a key role in cell growth, differentiation, attachment, and cell migration. The α-chains contain GXY repeats. Glycine (G) is a small amino acid that fits well in the triple helix. X and Y are typically proline and hydroxyproline, which is critical for collagen stability. Type I is the most common fibrillar collagen (90%) and is mostly found in skin, bone, tendons, and other connective tissues.
Rat tail collagen I can be prepared as a clear gel providing a 3D matrix or surface coated on tissue culture plates as a substrate for culturing primary cells such as keratinocytes and hepatocytes.
Specifications
| 4 mg/mL | |
| 25 mL | |
| Rat | |
| ≤10 EU/mL, ≤ 10 EU/mL | |
| Native | |
| Collagen | |
| Gibco™ |
| Cell Culture | |
| Collagen | |
| Store in refrigerator (2–8°C) and protect from light. | |
| Wet Ice | |
| Liquid | |
| Extracellular Matrix & Cell Adhesion |
For Research Use Only. Not for use in diagnostic procedures.