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Thermo Scientific Chemicals Chloroform, Molecular Biology Reagent

Catalog No. AAJ67241AP
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2.5 L
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AAJ67241AP 500 mL
AAJ67241K2 1 L
AAJ67241K4 2.5 L
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Catalog No. AAJ67241AP Supplier Thermo Scientific Chemicals Supplier No. J67241AP
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This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.

Description

CAS: 67-66-3 | CHCl3 | 119.37 g/mol

Chloroform is a common laboratory reagent favored for use as a solvent due to the compounds relative unreactivity and miscibility with most organic compounds. Chloroform is also used in organic synthesis as a source for CCl2. In the swine tracheal smooth muscle, chloroform has been demonstrated to directly and in a concentration dependent manner induce contractions. It has been observed that Chloroform can release Ca2+ from ryanodine sensitive receptors in chloroform-induced contraction in swine tracheal smooth muscle. At concentrations of 100 and 250 ppm in mouse splenocyte, basal proliferation was increased yet a decrease in circulating neutrophils was documented.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Chloroform is a common laboratory reagent favored for use as a solvent due to the compounds relative unreactivity and miscibility with most organic compounds. Chloroform is also used in organic synthesis as a source for CCl2. In the swine tracheal smooth muscle, chloroform has been demonstrated to directly and in a concentration dependent manner induce contractions. It has been observed that Chloroform can release Ca2+ from ryanodine sensitive receptors in chloroform-induced contraction in swine tracheal smooth muscle. At concentrations of 100 and 250 ppm in mouse splenocyte, basal proliferation was increased yet a decrease in circulating neutrophils was documented.

Solubility
Soluble in water at 20°C 8 g/L.

Notes
Stabilized with approx. 50 ppm amylene

Chemical Identifiers

CAS 67-66-3
Molecular Formula CHCl3
Molecular Weight (g/mol) 119.37
MDL Number MFCD00000826
InChI Key HEDRZPFGACZZDS-UHFFFAOYSA-N
Synonym trichloromethane, formyl trichloride, methane, trichloro, trichloroform, methane trichloride, methenyl trichloride, methyl trichloride, trichlormethan, chloroforme, cloroformio
PubChem CID 6212
ChEBI CHEBI:35255
SMILES ClC(Cl)Cl

Specifications

Melting Point -63°C
Color Colorless
Density 1.492 g/mL
Boiling Point 61°C
Quantity 500 mL
Odor Characteristic
Physical Form Liquid
Refractive Index 1.446
UN Number UN1888
Beilstein 1731042
Merck Index 14,2141
Solubility Information Soluble in water at 20°C 8g/L.
IUPAC Name chloroform
Formula Weight 119.38
Chemical Name or Material Chloroform, Molecular Biology Reagent
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Safety and Handling

Hazard Category H302-H315-H319-H331-H335-H336-H351-H361d-H373
Hazard Statement GHS H Statement
H351-H373-H302-H315
Suspected of causing cancer.
May cause damage to organs through prolonged or repeated exposure.
Harmful if swallowed.
Causes skin irritation.
Precautionary Statement P201-P202-P260-P264b-P270-P271-P280i-P281-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P330-P332+P313-P362-P501c
DOTInformation Transport Hazard Class: 6.1; Packaging Group: III; Proper Shipping Name: CHLOROFORM
EINECSNumber 200-663-8
RTECSNumber FS9100000
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only