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  6. Invitrogen™ CellROX™ Reagent for oxidative stress detection

Invitrogen™ CellROX™ Reagent for oxidative stress detection

Catalog No. C10448
Encompass
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C10448 Orange, Far-Red, Green
C10444 Green
C10443 Orange
C10422 Deep Red
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Catalog No. C10448 Supplier Invitrogen™ Supplier No. C10448
  • ONLINE EXCLUSIVE PRICE
    $690.00
    $565.80 / Each

    Save $124.20

    18.0% Off The following deviations and disclosures may produce prices below stated discounts but will not trigger price reductions: Price shown reflects a temporary, promotional price reduction. No other purchase or commercial obligation required to receive the reduced price. Price may change at any time. Promotional price valid on web orders only. Your contract pricing may differ. Other exclusions apply.

Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

Description

CellROX™ Reagents are novel fluorogenic probes for measuring cellular oxidative stress in both live and fixed cell imaging.

The CellROX™ Reagents are novel fluorogenic probes for measuring cellular oxidative stress in live cells. These cell-permeant dyes exhibit bright fluorescence upon oxidation by reactive oxygen species (ROS). (See table below for details of each reagent.)

The CellROX™ reagents are:

  • Optimized for detection of oxidative stress in live cells and may be added directly to serum-containing growth media
  • Provided as a stable, ready-to-use DMSO solutions with simple protocols, compatible with standard workflows in fluorescence microscopy
  • Compatible with a variety of detection platforms, including traditional fluorescence microscopy, high content screening (HCS), and flow cytometry

Oxidative stress results from an imbalance between the production of reactive oxygen species (ROS) and the ability of cells to scavenge them. ROS play an important role in the progression of several diseases, including inflammation, atherosclerosis, aging, and age-related degenerative disorders.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

Order Info

Shipping Condition: Wet Ice

Specifications

Color Orange, Far-Red, Green
Format Frozen
Quantity 1 kit

Frequently Asked Questions (FAQs)

What dyes can I use to detect reactive oxygen species (ROS) in my bacteria?

Many dyes that are used on mammalian cells have also been shown to be useful in bacterial cells. For example, CellROX Deep Red Reagent has been shown to work in B. subtilis (see Reference: http://www-brs.ub.ruhr-uni-bochum.de/netahtml/HSS/Diss/RaatschenNadja/diss.pdf). If you are interested in a particular dye, but are not sure if it will work on your bacteria, literature searches are the best way to check to see if it has been tested. If not, then it may be worth testing yourself.

For Research Use Only. Not for use in diagnostic procedures.