Effective against gram negative and gram positive microorganisms. Penicillin interferes with the final stage of synthesis of the bacterial cell wall. Streptomycin inhibits elongation at transpeptidation step during protein synthesis and binds to 30S subunit, causing misreading. Common working concentration for penicillin is 100 U/mL; for Streptomycin: 100 g/mL. Penicillin/Streptomycin is a broad spectrum bacteriostatic with activity against gram negative and gram-positive organisms. ****This item is required to ship on dry ice. Overnight Shipping required, For Research Use Only (RUO)