missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Bortezomib, 98%
Bortezomib (CAS # 179324-69-7) is an inhibitor of protein degradation pathways. | CAS: 179324-69-7 | C19H25BN4O4 | 384.243 g/mol
$481.93 - $840.29
Identifiants chimiques
| CAS | 179324-69-7 |
|---|---|
| Molecular Formula | C19H25BN4O4 |
| Molecular Weight (g/mol) | 384.243 |
| MDL Number | MFCD09056737 |
| InChI Key | GXJABQQUPOEUTA-RDJZCZTQSA-N |
| Synonym | bortezomib, velcade, bortezomib ps-341, dpba, pyz-phe-boroleu, unii-69g8bd63pp, velcade tn, bortezomib velcade, 1r-3-methyl-1-2s-1-oxo-3-phenyl-2-pyrazinylcarbonyl amino propyl amino butyl boronic acid, 1r-3-methyl-1-2s-3-phenyl-2-pyrazine-2-carbonylamino propanoyl amino butyl boronic acid |
| PubChem CID | 387447 |
| ChEBI | CHEBI:52717 |
| IUPAC Name | [(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid |
| SMILES | B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O |
| Numéro de catalogue | Numéro du manufacturier. | Quantity | Prix | Quantité | |||||
|---|---|---|---|---|---|---|---|---|---|
| Numéro de catalogue | Numéro du manufacturier. | Quantity | Prix | Quantité | |||||
|
AAJ60378MA
|
Thermo Scientific Chemicals
J60378MA |
10 mg |
chaque for $481.93
|
|
Connectez-vous ou enregistrez-vous pour vérifier votre prix et la disponibilité.
|
||||
|
AAJ60378MB
|
Thermo Scientific Chemicals
J60378MB |
25 mg |
chaque for $840.29
|
|
Connectez-vous ou enregistrez-vous pour vérifier votre prix et la disponibilité.
|
||||
Description
A potent, highly selective and reversible inhibitor of the 20S proteasome, Bortezomib is used as an antineoplastic agent, which controls the growth of cancer cells. It is also useful in the treatment of multiple myeloma.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Bortezomib is an antineoplastic compound derived from boronic acid
• Bortezomib reversibly inhibits the 26S proteostome that maintains cell cycle pathways related to growth and division
• Bortezomib is an inhibitor of NF-κB, a factor that is constituitively active in some cancers
Application
• Bortezomib is suitable for use in the research of multiple myeloma and lymphomas, and for use in the research of protein degradation pathways
• Bortezomib is intended for in vitro and biochemical applications
Identifiants chimiques
| 179324-69-7 | |
| 384.243 | |
| GXJABQQUPOEUTA-RDJZCZTQSA-N | |
| 387447 | |
| [(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid |
| C19H25BN4O4 | |
| MFCD09056737 | |
| bortezomib, velcade, bortezomib ps-341, dpba, pyz-phe-boroleu, unii-69g8bd63pp, velcade tn, bortezomib velcade, 1r-3-methyl-1-2s-1-oxo-3-phenyl-2-pyrazinylcarbonyl amino propyl amino butyl boronic acid, 1r-3-methyl-1-2s-3-phenyl-2-pyrazine-2-carbonylamino propanoyl amino butyl boronic acid | |
| CHEBI:52717 | |
| B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O |
Spécifications
| 179324-69-7 | |
| Brown to White | |
| MFCD09056737 | |
| UN3249 | |
| bortezomib, velcade, bortezomib ps-341, dpba, pyz-phe-boroleu, unii-69g8bd63pp, velcade tn, bortezomib velcade, 1r-3-methyl-1-2s-1-oxo-3-phenyl-2-pyrazinylcarbonyl amino propyl amino butyl boronic acid, 1r-3-methyl-1-2s-3-phenyl-2-pyrazine-2-carbonylamino propanoyl amino butyl boronic acid | |
| GXJABQQUPOEUTA-RDJZCZTQSA-N | |
| [(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid | |
| 387447 | |
| 384.24 | |
| Powder |
| 139°C to 143°C | |
| C19H25BN4O4 | |
| 10 mg | |
| 14,1351 | |
| Soluble in chloroform,dimethyl sulfoxide,ethanol and methanol. | |
| B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O | |
| 384.243 | |
| CHEBI:52717 | |
| 99% | |
| Bortezomib |
Sécurité et manipulation
GHS H Statement
H300-H310-H330-H372
Fatal if swallowed.
Fatal in contact with skin.
Fatal if inhaled.
Causes damage to organs through prolonged or repeated exposure.
P260-P264b-P270-P271-P280-P284-P301+P310-P302+P352-P304+P340-P310-P312-P314-P330-P361-P363-P501c
H301+H311-H330-H372
DOTInformation : Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: MEDICINE, SOLID, TOXIC, N.O.S.
missing translation for 'rtecsNumber' : ED7771666
missing translation for 'tsca' : No
Recommended Storage : Store at -20°C
RUO – Research Use Only