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Bestatin hydrochloride, 98%, Thermo Scientific Chemicals

$183.59 - $570.19

Chemical Identifiers

CAS 65391-42-6
Molecular Formula C16H25ClN2O4
Molecular Weight (g/mol) 344.836
MDL Number MFCD00058004
InChI Key XGDFITZJGKUSDK-UDYGKFQRSA-N
Synonym bestatin hydrochloride, n-2s,3r-3-amino-2-hydroxy-4-phenylbutyryl-l-leucine hydrochloride, ubenimex hydrochloride, bestatin hcl, bestatin monohydrochloride, c16h24n2o4.hcl, bestatin hydrochloride hplc, bestatin, 2s,3r-3-amino-2-hydroxy-4-phenylbutanoyl-l-leucine hydrochloride
PubChem CID 11957481
IUPAC Name (2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid;hydrochloride
SMILES CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O.Cl
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ60384LB0
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Thermo Scientific Chemicals
J60384LB0
5 mg
Each for $183.59
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AAJ60384MB
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Thermo Scientific Chemicals
J60384MB
25 mg
Each for $570.19
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Description

Description

Bestatin is an inhibitor of amino peptidases and a potent, irreversible inhibitor of LTA4 hydrolase. It inhibits the amino peptidase activity of LTA4 hydrolase with a Ki value of 201 nM. It offers promise as a novel analgesic because it protects endogenous opioid peptides against degradation. It does not inhibit carboxypeptidases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Bestatin is an inhibitor of amino peptidases and a potent, irreversible inhibitor of LTA4 hydrolase. It inhibits the amino peptidase activity of LTA4 hydrolase with a Ki value of 201 nM. It offers promise as a novel analgesic because it protects endogenous opioid peptides against degradation. It does not inhibit carboxypeptidases.

Solubility
Soluble in water (4 mg/ml, warm), DMSO (>25 mg/ml), methanol, acetic acid, dimethyl formamide, and 100% ethanol.

Notes
Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents.
Specifications

Chemical Identifiers

65391-42-6
344.836
XGDFITZJGKUSDK-UDYGKFQRSA-N
11957481
CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O.Cl
C16H25ClN2O4
MFCD00058004
bestatin hydrochloride, n-2s,3r-3-amino-2-hydroxy-4-phenylbutyryl-l-leucine hydrochloride, ubenimex hydrochloride, bestatin hcl, bestatin monohydrochloride, c16h24n2o4.hcl, bestatin hydrochloride hplc, bestatin, 2s,3r-3-amino-2-hydroxy-4-phenylbutanoyl-l-leucine hydrochloride
(2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid;hydrochloride

Specifications

65391-42-6
White
MFCD00058004
4628066
Soluble in water (4mg/ml,warm),DMSO (>25mg/ml),methanol,acetic acid,dimethyl formamide,and 100% ethanol.
CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O.Cl
344.836
344.87
Powder
216°C to 218°C
C16H25ClN2O4
5 mg
bestatin hydrochloride, n-2s,3r-3-amino-2-hydroxy-4-phenylbutyryl-l-leucine hydrochloride, ubenimex hydrochloride, bestatin hcl, bestatin monohydrochloride, c16h24n2o4.hcl, bestatin hydrochloride hplc, bestatin, 2s,3r-3-amino-2-hydroxy-4-phenylbutanoyl-l-leucine hydrochloride
XGDFITZJGKUSDK-UDYGKFQRSA-N
(2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoic acid;hydrochloride
11957481
98%
Bestatin hydrochloride
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Safety and Handling

Safety and Handling

TSCA : No

Recommended Storage : Ambient temperatures

SDS
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RUO – Research Use Only