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  8. Benzyl carbazate, 98+%

Benzyl carbazate, 98+%

Catalog No. p-7020897
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AAA1300506 5 g
AAA1300514 25 g
AAA1300522 100 g
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Catalog No. AAA1300506 Supplier Thermo Scientific Chemicals Supplier No. A1300506
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Description

CAS: 5331-43-1 | C8H10N2O2 | 166.18 g/mol

Benzyl carbazate is used as a reagent for preparation of benzyloxycarbonyl (Z, Cbz) hydrazides of carboxylic acids, particularly N-protected amino acids. Subsequent hydrogenolysis gives the hydrazide which can be converted to the azide for coupling with a further amino acid residue by the azide method. It is also used in the preparation of simple acyl or sulfonyl hydrazides avoiding diacylation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Benzyl carbazate is used as a reagent for preparation of benzyloxycarbonyl (Z, Cbz) hydrazides of carboxylic acids, particularly N-protected amino acids. Subsequent hydrogenolysis gives the hydrazide which can be converted to the azide for coupling with a further amino acid residue by the azide method. It is also used in the preparation of simple acyl or sulfonyl hydrazides avoiding diacylation.

Solubility
Soluble in water (slightly), methanol and DMSO.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Handle under inert gas. Protect from moisture. Incompatible with strong oxidizing agents.

Chemical Identifiers

CAS 5331-43-1
Molecular Formula C8H10N2O2
Molecular Weight (g/mol) 166.18
MDL Number MFCD00041890
InChI Key RXUBZLMIGSAPEJ-UHFFFAOYSA-N
Synonym benzyl carbazate, benzyl hydrazinecarboxylate, hydrazinecarboxylic acid, phenylmethyl ester, carbobenzoxyhydrazide, carbazic acid, benzyl ester, benzyloxycarbonyl hydrazide, benzylcarbazate, benzyloxy carbonyl hydrazine, n-cbz-hydrazine, unii-h7gm2h55tc
PubChem CID 79242
IUPAC Name benzyl N-aminocarbamate
SMILES C1=CC=C(C=C1)COC(=O)NN

Specifications

Melting Point 66°C to 70°C
Quantity 5 g
Beilstein 1952982
Solubility Information Soluble in water (slightly),methanol and DMSO.
Formula Weight 166.18
Percent Purity ≥98%
Chemical Name or Material Benzyl carbazate

Safety and Handling

Hazard Category Danger
Hazard Statement GHS H Statement
H318-H335-H315
Causes serious eye damage.
May cause respiratory irritation.
Causes skin irritation.
Precautionary Statement GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
EINECSNumber 226-230-3
RTECSNumber MV1724950
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only