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anti-PEN2 Polyclonal, Invitrogen™
PEN2 Polyclonal antibody PA1-10293 from Thermo Scientific Pierce specifically detects PEN2 in Hamster and Mouse samples, and it is validated for WB
Supplier: METTLER TOLEDO 30601008
Description
Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase.
Host Species: Rabbit
Isotype: IgG
Species Reactivity: Hamster, Human, Mouse
Formulation: 200μg of Affinity chromatography purified antibody ;
Immunogen: Synthetic peptide, conjugated to KLH, corresponding to the 11 most N-terminal residues of human Pen-2.
Synonyms: hPen2-N
Uniprot Accession: Q9NZ42, Q9CQR7
Entrez Gene ID: 66340, 55851
PA1-10293 detects PEN2 in Hamster and Mouse samples. PA1-10293 has been successfully used in WB procedures. The immunogen is Synthetic peptide, conjugated to KLH, corresponding to the 11 most N-terminal residues of human Pen-2.
Western Blotting
Specifications
| PEN2 | |
| Unconjugated | |
| Synthetic peptide, conjugated to KLH, corresponding to the 11 most N-terminal residues of human Pen-2. | |
| Primary | |
| Store at -20°C. Avoid Freeze/Thaw Cycles | |
| IgG |
| Polyclonal | |
| Rabbit | |
| 200 μg | |
| Hamster, Human, Murine | |
| Purified |