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Alfa Aesar™ Angiotensin II (human)

$124.59 - $456.47

Chemical Identifiers

CAS 4474-91-3
Molecular Formula C50H71N13O12
Molecular Weight (g/mol) 1046.197
MDL Number MFCD00133092
InChI Key CZGUSIXMZVURDU-JZXHSEFVSA-N
Synonym angiotensin ii, human angiotensin ii, angiotensin ii human, angiotensin ii mouse, ang ii, 5-isoleucine-angiotensin ii, 5-l-isoleucineangiotensin ii, angiotensin ii human, giapreza, ile 5-angiotensin ii
PubChem CID 172198
ChEBI CHEBI:2719
IUPAC Name (3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(1S)-1-carboxy-2-phenylethyl]carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-me
SMILES CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ60866LB0 View Documents Alfa Aesar™
J60866LB0
5mg Each for $124.59
 
AAJ60866MB View Documents Alfa Aesar™
J60866MB
25mg Each for $456.47
 
Description

Description

Applications
Ang II stimulates angiogenesis and increases microvessel density. In addition, the renin-angiotensin and nitric oxide-generating systems appear to interract in the regulation of cardiovascular function. Angiotensin (Ang) II is a peptide which plays an important role in the regulation of blood pressure and has strong vasoconstrictive effects. It also stimulates the release of aldosterone from the adrenal gland and inhibits adenylate cyclase activity. It also increases the entry of Ca2+ in heart muscle via voltage-sensitive channels and activates myosin light chain kinase (MYLK). It also elicits an increase in voltage-dependent delayed rectifier K+ current in neurons and activates JAK2 in smooth muscle cells.

Solubility
Soluble in Water (25 mg/ml), and 5% Acetic Acid (1 mg/ml).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -20°C. keep away from Strong acids, Strong bases .
Specifications

Chemical Identifiers

4474-91-3
1046.197
CZGUSIXMZVURDU-JZXHSEFVSA-N
172198
(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(1S)-1-carboxy-2-phenylethyl]carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-me
C50H71N13O12
MFCD00133092
angiotensin ii, human angiotensin ii, angiotensin ii human, angiotensin ii mouse, ang ii, 5-isoleucine-angiotensin ii, 5-l-isoleucineangiotensin ii, angiotensin ii human, giapreza, ile 5-angiotensin ii
CHEBI:2719
CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N

Specifications

White
4474-91-3
MFCD00133092
CZGUSIXMZVURDU-JZXHSEFVSA-N
(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(1S)-1-carboxy-2-phenylethyl]carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-me
172198
1046.19
Angiotensin II (human)
5mg
C50H71N13O12
angiotensin ii, human angiotensin ii, angiotensin ii human, angiotensin ii mouse, ang ii, 5-isoleucine-angiotensin ii, 5-l-isoleucineangiotensin ii, angiotensin ii human, giapreza, ile 5-angiotensin ii
CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N
1046.197
CHEBI:2719
Powder
Safety and Handling

Safety and Handling

RTECSNumber : BW2165000

Recommended Storage : −30° to −10°C