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Amiodarone hydrochloride

Catalog No. AAJ6045603
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Catalog No. AAJ6045603 Supplier Thermo Scientific Chemicals Supplier No. J6045603
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Description

A non-selective ion channel blocker; also an antiarrhythmic agent | CAS: 19774-82-4 | C25H30ClI2NO3 | 681.778 g/mol

Amiodarone induces an immediate influx of Ca2+ in Saccharomyces cerevisiae, followed by mitochondrial fragmentation and cell death.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Amiodarone induces an immediate influx of Ca2+ in Saccharomyces cerevisiae, followed by mitochondrial fragmentation and cell death.

Solubility
Soluble in chloroform, methanol.

Notes
Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat. Store in refrigerator.

Chemical Identifiers

CAS 19774-82-4
Molecular Formula C25H30ClI2NO3
Molecular Weight (g/mol) 681.778
MDL Number MFCD00069204
InChI Key ITPDYQOUSLNIHG-UHFFFAOYSA-N
Synonym amiodarone hydrochloride, amiodarone hcl, amiodar, nexterone, pacerone, amiodaronum hydrochloride, ritmocardyl, rythmarone, angoron
PubChem CID 441325
IUPAC Name (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone;hydrochloride
SMILES CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I.Cl

Specifications

Melting Point 156°C to 163°C
Color White
Quantity 1 g
Merck Index 14,482
Solubility Information Soluble in chloroform,methanol.
Formula Weight 681.77
Physical Form Powder
Chemical Name or Material Amiodarone hydrochloride

Safety and Handling

Hazard Category H312+H332-H361d-H373
Precautionary Statement P201-P202-P260-P271-P281-P302+P352-P304+P340-P308+P313-P312-P363-P501c
EINECSNumber 243-293-2
RTECSNumber OB1361000
TSCA No
Recommended Storage Keep cold

RUO – Research Use Only