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5-(Trifluoromethoxy)isatin, 98%

CAS: 169037-23-4 | C9H4F3NO3 | 231.13 g/mol

Supplier:  Thermo Scientific Chemicals B2549403

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Catalog No. AAB2549403


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Description

Description

5-(Trifluoromethoxy)isatin is used as a reactant for preparation of oxindole derivatives as TAk1 kinase inhibitors and of isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors. It is also used as a reactant for synthesis of 3-substituted 2-indolinone RET kinase inhibitors and for preparation of indolone acetamides as antiseizure agents.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-(Trifluoromethoxy)isatin is used as a reactant for preparation of oxindole derivatives as TAk1 kinase inhibitors and of isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors. It is also used as a reactant for synthesis of 3-substituted 2-indolinone RET kinase inhibitors and for preparation of indolone acetamides as antiseizure agents.

Solubility
Insoluble in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
Specifications

Specifications

5-(Trifluoromethoxy)isatin
170°C to 172°C
MFCD00192524
5-trifluoromethoxy isatin, 5-trifluoromethoxy indoline-2,3-dione, 5-trifluoromethoxy-1h-indole-2,3-dione, 5-trifluoromethoxyisatin, 1h-indole-2,3-dione, 5-trifluoromethoxy, 5-trifluoromethoxy-2,3-indolinedione, buttpark 34\07-90, acmc-209dz9, d0zr2t
XHAJMVPMNOBILF-UHFFFAOYSA-N
5-(trifluoromethoxy)-1H-indole-2,3-dione
2732752
98%
169037-23-4
C9H4F3NO3
1 g
Insoluble in water.
C1=CC2=C(C=C1OC(F)(F)F)C(=O)C(=O)N2
231.13
231.13

Chemical Identifiers

169037-23-4
231.13
XHAJMVPMNOBILF-UHFFFAOYSA-N
2732752
C1=CC2=C(C=C1OC(F)(F)F)C(=O)C(=O)N2
C9H4F3NO3
MFCD00192524
5-trifluoromethoxy isatin, 5-trifluoromethoxy indoline-2,3-dione, 5-trifluoromethoxy-1h-indole-2,3-dione, 5-trifluoromethoxyisatin, 1h-indole-2,3-dione, 5-trifluoromethoxy, 5-trifluoromethoxy-2,3-indolinedione, buttpark 34\07-90, acmc-209dz9, d0zr2t
5-(trifluoromethoxy)-1H-indole-2,3-dione
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Safety and Handling

Safety and Handling

TSCA : No

Recommended Storage : Ambient temperatures

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