Thermo Scientific™ 5 L DynaDrive™ Bioreactor Bioprocess Consumable (BPC) Traditional Probe Sensor Version

Description

The Thermo Scientific™ DynaDrive™ 5 L BioProcess Container (BPC), PROSUT00181-I, is a pre-irradiated, single-use bioreactor container designed for upstream process development and scale-down modeling. Configured with a traditional single-use pH probe and a dissolved oxygen (DO) probe cap, this BPC provides flexibility for laboratories that prefer traditional probe sensors while maintaining scalability across the DynaDrive family of reactors.

Manufactured with Thermo Scientific™ Aegis™ 5-14 bioprocess film and an integrated multi-impeller DynaDrive drivetrain, the PROSUT00181-I BPC delivers efficient mixing, robust gas transfer, and process performance aligned with the full DynaDrive platform from bench scale through 5,000 L working volume.

Key features and benefits

• Mixing, sparging, and geometry principles of larger DynaDrive bioreactors for confident scale-up into DynaDrive family
• Flexible 5:1 turndown ratio (1–5 L)
• Cuboid design with natural fluid baffling effects
• Configured with a traditional single-use pH probe and a dissolved oxygen (DO) probe cap
• Multi-impeller drivetrain and enhanced drilled-hole sparger (DHS) support high cell density cultures with effective DO and CO2 control
• Gamma-irradiated single-use BPC eliminates the need for autoclaving, reducing turnaround time and contamination risk versus traditional glass bioreactors
• Fed-batch & perfusion capable standard design

Typical applications

• Upstream process development and optimization
• Scale-down modeling for fed-batch or perfusion processes
• Media and feed screening
• Seed train and N-1 process development
• Transition from glass benchtop bioreactors to single-use systems

Product specifications (highlights)

• Working volume: 1–5 L (5:1 turndown ratio)
• Film: Thermo Scientific Aegis 5-14 bioprocess film
• Agitation: Multi-impeller drivetrain
• Sparging: Enhanced drilled-hole sparger for efficient oxygen transfer and CO2 stripping and open pipe sparger
• Sensors: Built-in single-use Hamilton pH and Hamilton DO probe cap (traditional probe sensors)
• Sterilization: Gamma-irradiated, single-use, ready-to-install
• Compatible with 5 L DynaDrive single-use bioreactor stands configured for traditional sensors (DDB0005.1021)
• Compatible with 5L DynaDrive Traditional Sensor Probe Kit (F110-2759-001)

Designed for the DynaDrive ecosystem

The PROSUT00181-I BPC is part of the Thermo Scientific DynaDrive Single-Use Bioreactor platform, providing a direct and consistent scalability path from bench-scale development to large-scale manufacturing.