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5-chloro-2'-deoxyuridine, MP Biomedicals™
Readily incorporated, following phosphorylation, into newly synthesized DNA in place of thymidine. MP Biomedicalsâ 5-chloro-2'-deoxyuridine (CldU) can be used as labeling substrate, thymidine analog, or to identify sites of DNA replication. Visible absorb
Supplier: MP Biomedicals Inc 0210547891
Description
- Used as a thymidine analog to study the miscoding potential of hypochlorous acid damage to DNA and DNA precursors
- When used with antibody based immunofluorescent imaging, may be used in protocols to identify sites of DNA replication
- May be used as a labeling substrate in conjunction with other halogenated uridine labeling substrates, such as bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU)
Specifications
| 50-90-8 | |
| C9H11ClN2O5 | |
| 5-chloro-2'-deoxyuridine | |
| NJCXGFKPQSFZIB-XVMARJQXSA-N | |
| 5-chloro-1-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione | |
| 13831089 | |
| Powder |
| 166°C to 176°C | |
| 1 g | |
| Soluble in 1M NH4OH (20mg/1ml, colorless solution). | |
| C1C(C(OC1N2C=C(C(=O)NC2=O)Cl)CO)O | |
| 262.646 | |
| 262.6 |
Chemical Identifiers
| 50-90-8 | |
| 262.646 | |
| 5-chloro-2'-deoxyuridine | |
| 5-chloro-1-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
| C9H11ClN2O5 | |
| NJCXGFKPQSFZIB-XVMARJQXSA-N | |
| 13831089 | |
| C1C(C(OC1N2C=C(C(=O)NC2=O)Cl)CO)O |
Safety and Handling
Recommended Storage : Store at 0°C.