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  7. 4-Hydroxy-1-methylpiperidine, 98%

4-Hydroxy-1-methylpiperidine, 98%

Catalog No. p-7044439
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Quantity:
100 g
500 g
Catalog No. Quantity
AAL0641522 100 g
AAL0641536 500 g
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Catalog No. AAL0641522

Supplier: Thermo Scientific Chemicals L0641522

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Description

CAS: 106-52-5 | C6H13NO | 115.176 g/mol

4-Hydroxy-1-methylpiperidine is used as reactant for optimization of Novobiocin scaffold to product antitumor agents, substitution about the rigidifying ring for histamine H4 receptor antagonist synthesis. It is also used as a reactant in the synthesis of CaMKII, VEGFR and FGFR kinase inhibitors and Phosphoinositide-3-kinase, Protein lysine methyltransferase G9a inhibitors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Hydroxy-1-methylpiperidine is used as reactant for optimization of Novobiocin scaffold to product antitumor agents, substitution about the rigidifying ring for histamine H4 receptor antagonist synthesis. It is also used as a reactant in the synthesis of CaMKII, VEGFR and FGFR kinase inhibitors and Phosphoinositide-3-kinase, Protein lysine methyltransferase G9a inhibitors.

Solubility
Soluble in water.

Notes
Hygroscopic. Store under dry inert gas. Store away from moisture and oxidizing agents. Incompatible with water and oxidizing agents. Store at 4°C.

Chemical Identifiers

CAS 106-52-5
Molecular Formula C6H13NO
Molecular Weight (g/mol) 115.176
MDL Number MFCD00006500
InChI Key BAUWRHPMUVYFOD-UHFFFAOYSA-N
Synonym 4-hydroxy-1-methylpiperidine, n-methyl-4-piperidinol, 1-methyl-4-piperidinol, 4-hydroxy-n-methylpiperidine, n-methyl-4-hydroxypiperidine, 4-piperidinol, 1-methyl, 1-methyl-4-hydroxypiperidine, n-methylpiperidol, n-methyl-4-hydroxy piperidine, 4-hydroxy-1-methyl-piperidine
PubChem CID 66048
IUPAC Name 1-methylpiperidin-4-ol
SMILES CN1CCC(CC1)O

Specifications

Melting Point 26°C to 30°C
Density 0.98
Boiling Point 198°C to 200°C
Flash Point 87°C (188°F)
Refractive Index 1.479
Quantity 100 g
Beilstein 103024
Sensitivity Hygroscopic
Solubility Information Soluble in water.
Formula Weight 115.18
Percent Purity 98%
Chemical Name or Material 4-Hydroxy-1-methylpiperidine
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Safety and Handling

Hazard Category H315-H319-H335
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber 203-406-8
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only