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  7. 4-Fluorophthalic anhydride, 98%

4-Fluorophthalic anhydride, 98%

Catalog No. p-7025712
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Quantity:
25 g
5 g
Catalog No. Quantity
AAB2135206 5 g
AAB2135214 25 g
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Catalog No. AAB2135206

Supplier: Thermo Scientific Chemicals B2135206

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Description

CAS: 319-03-9 | C8H3FO3 | 166.11 g/mol

4-Fluorophthalic anhydride is used in the preparation of 5-fluoro-2-pyridin-3-ylmethyl-isoindole-1,3-dione by reacting with C-pyridin-3-yl-methylamine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Fluorophthalic anhydride is used in the preparation of 5-fluoro-2-pyridin-3-ylmethyl-isoindole-1,3-dione by reacting with C-pyridin-3-yl-methylamine.

Solubility
Soluble in sodium hydroxide.

Notes
Moisture sensitive. Incompatible with strong oxidizing agents.

Chemical Identifiers

CAS 319-03-9
Molecular Formula C8H3FO3
Molecular Weight (g/mol) 166.11
MDL Number MFCD00191363
InChI Key XVMKZAAFVWXIII-UHFFFAOYSA-N
Synonym 4-fluorophthalic anhydride, 5-fluoroisobenzofuran-1,3-dione, 5-fluoro-1,3-isobenzofurandione, 1,3-isobenzofurandione, 5-fluoro, 4-fluorophthalicanhydride, 4-fluorophthalic acid anhydride, 5-fluoro-1,3-dihydro-2-benzofuran-1,3-dione, 4-fluorobenzene-1,2-dicarboxylic anhydride, 5-fluoro-isobenzofuran-1,3-dione
PubChem CID 67572
IUPAC Name 5-fluoro-2-benzofuran-1,3-dione
SMILES FC1=CC=C2C(=O)OC(=O)C2=C1

Specifications

Melting Point 74°C to 79°C
Density 1.5
Boiling Point 147°C to 149°C (20 mmHg)
Quantity 5 g
Beilstein 131281
Sensitivity Moisture sensitive
Solubility Information Soluble in sodium hydroxide.
Formula Weight 166.11
Percent Purity 98%
Chemical Name or Material 4-Fluorophthalic anhydride

Safety and Handling

Hazard Category H302-H315-H317-H319-H334-H335
Hazard Statement GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P270-P271-P272-P280-P285-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P333+P313-P342+P311-P362-P501c
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only