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4-Aminobutyric acid, 99+%, Thermo Scientific Chemicals
4-Aminobutyric acid, 99+%, CAS # 56-12-2, also known as γ-Aminobutyric acid, is an amino acid that shows inhibitory activities against neurotransmitters, including GABA.
Supplier: Thermo Scientific Chemicals 103285000
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• 4-Aminobutyric acid is a γ-amino acid and monocarboxylic acid derived from butyric acid
• It is an amino acid that shows inhibitory activities against neurotransmitters, including GABA, and acts by binding GABA-A receptor and inhibiting the activity of signal-receiving neurons
• This compound, converted from neurotransmitter glutamate, is essential to regulate neuronal excitability
• It binds to GABA-A and GABA-B receptors, causing ion channel opening, hyperpolarization, and eventually inhibition of neurotransmission
Applications
• 4-Aminobutyric acid has been used in the preparation of GABA–BSA (bovine serum albumin)–GA (glutaraldehyde) conjugate, which is used as a control for immunohistochemical experiments
• It is used, in vivo, to detect GABA neurotransmitter by magnetic resonance spectroscopy
• This compound increases the production of short-chain fatty acids and decreases pH values in mouse colon
• Some in vivo experiments, using rats, mice, and pigs, demonstrated that 4-Aminobutyric acid can modulate intestinal fluid secretion, blood flow and ulceration
Specifications
| 197°C to 204°C | |
| 99+% | |
| 99.0 | |
| White | |
| C4H9NO2 | |
| H2N(CH2)3CO2H | |
| 04,413 | |
| 15,425 | |
| 4-aminobutyric acid, gaba, gamma-aminobutyric acid, piperidic acid, piperidinic acid, aminalon, gaballon, gammalon, mielogen, butanoic acid, 4-amino | |
| BTCSSZJGUNDROE-UHFFFAOYSA-N | |
| 4-aminobutanoic acid | |
| 119 | |
| 95% min. (c=10, 2N HCl, 430nm) 1cm cell | |
| ≥99% | |
| Crystalline Powder |
| 4-Aminobutyric acid | |
| 56-12-2 | |
| 100.0 | |
| 99+% | |
| Authentic | |
| MFCD00008226 | |
| 0.5% max. | |
| Plastic Bottle | |
| Solubility in water: very soluble. Other solubilities: slightly soluble in common solvents | |
| C(CC(=O)O)CN | |
| 103.12 | |
| CHEBI:16865 | |
| 103.12 | |
| 500 g |
Chemical Identifiers
| 56-12-2 | |
| 103.12 | |
| BTCSSZJGUNDROE-UHFFFAOYSA-N | |
| 119 | |
| 4-aminobutanoic acid |
| C4H9NO2 | |
| MFCD00008226 | |
| 4-aminobutyric acid, gaba, gamma-aminobutyric acid, piperidic acid, piperidinic acid, aminalon, gaballon, gammalon, mielogen, butanoic acid, 4-amino | |
| CHEBI:16865 | |
| C(CC(=O)O)CN |
Safety and Handling
EINECSNumber : 200-258-6
RTECSNumber : ES6300000
TSCA : TSCA
RUO – Research Use Only