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  7. 4',5,7-Trihydroxyflavone, 97%

4',5,7-Trihydroxyflavone, 97%

Catalog No. p-7046573
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AAL15041MB 25 mg
AAL15041MC 100 mg
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Catalog No. AAL15041MB Supplier Thermo Scientific Chemicals Supplier No. L15041MB
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Description

CAS: 520-36-5 | C15H10O5 | 270.24 g/mol

4',5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4′,5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

Solubility
Soluble in dimethyl sulfoxide (27 mg/ml) or 1M potassium hydroxide (50mg/ml).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with and strong oxidizing agents.

Chemical Identifiers

CAS 520-36-5
Molecular Formula C15H10O5
Molecular Weight (g/mol) 270.24
MDL Number MFCD00006831
InChI Key KZNIFHPLKGYRTM-UHFFFAOYSA-N
Synonym apigenin, 5,7-dihydroxy-2-4-hydroxyphenyl-4h-chromen-4-one, chamomile, spigenin, versulin, apigenol, 4',5,7-trihydroxyflavone, apigenine, c.i. natural yellow 1, 5,7,4'-trihydroxyflavone
PubChem CID 5280443
ChEBI CHEBI:18388
IUPAC Name 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
SMILES OC1=CC=C(C=C1)C1=CC(=O)C2=C(O)C=C(O)C=C2O1

Specifications

Melting Point ∽315°C (decomposition)
Quantity 25 mg
Beilstein 262620
Merck Index 14,730
Solubility Information Soluble in dimethyl sulfoxide (27mg/ml) or 1M potassium hydroxide (50mg/ml).
Formula Weight 270.24
Percent Purity 97%
Chemical Name or Material 4',5,7-Trihydroxyflavone

Safety and Handling

Hazard Category H315-H319-H335
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber 208-292-3
RTECSNumber LK9276000
TSCA No
Recommended Storage Keep cold

RUO – Research Use Only