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Thermo Scientific Chemicals 3,4-Dihydroxy-L-phenylalanine, 98+%

Numéro de catalogue. AAA1131106
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AAA1131114 25 g
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Numéro de catalogue. AAA1131106 Fournisseur Thermo Scientific Chemicals Code fournisseur A1131106
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Description

3-(3,4-Dihydroxyphenyl)-L-alanine (levodopa orL-dopa), CAS # 59-92-7, is a dopamine precursor molecule. | CAS: 59-92-7 | C9H11NO4 | 197.19 g/mol

3,4-dihydroxy-L-phenylalanine (DOPA) is used as a cell adhesion molecule in serum-free cultures of anchorage-dependent mammalian cells. It is also used as an anticholinergic drug and used in the treatment of Parkinson's disease. It acts as an intermediate in the biosynthesis of other catecholamines (norepinephrine, epinephrine) and melanin. It acts as a precursor of dopamine product of tyrosine hydroxylase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • 3-(3,4-Dihydroxyphenyl)-L-alanine, or L-dopa, is converted to dopamine by DOPA decarboxylase in the body
  • Upon conversion to dopamine, it acts as an excitatory neurotransmitter

Applications

  • L-dopa is useful in the laboratory study of Parkinson's to replenish dopamine in depleted circuits
  • L-dopa has also been used for laboratory research on hypertension and melanocyte activity

Identifiants chimiques

CAS 59-92-7
Molecular Formula C9H11NO4
Molecular Weight (g/mol) 197.19
MDL Number MFCD00002598
InChI Key WTDRDQBEARUVNC-LURJTMIESA-N
Synonym levodopa, l-dopa, dopar, 3-hydroxy-l-tyrosine, 3,4-dihydroxy-l-phenylalanine, larodopa, bendopa, levopa, dihydroxy-l-phenylalanine, cidandopa
PubChem CID 6047
ChEBI CHEBI:15765
IUPAC Name (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid
SMILES N[C@@H](CC1=CC=C(O)C(O)=C1)C(O)=O

Spécifications

Melting Point ∼295°C (decomposition)
Beilstein 2215169
Merck Index 14,5464
Solubility Information Slightly soluble in water,dilute hydrochloric acid and formic acid. Insoluble in ethanol.
Quantity 5 g
Odor Odorless
Formula Weight 197.19
Percent Purity ≥98%
Sensitivity Light sensitive
Chemical Name or Material 3,4-Dihydroxy-L-phenylalanine

Sécurité et manipulation

Hazard Category H302-H315-H319
Hazard Statement GHS H Statement
H301
Toxic if swallowed.
Precautionary Statement P264b-P270-P280-P301+P312-P302+P352-P305+P351+P338-P330-P332+P313-P362-P501c
EINECSNumber 200-445-2
RTECSNumber AY5600000
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only