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Thermo Scientific Chemicals 2'-Deoxyuridine, 98+%
CAS: 951-78-0 | C9H12N2O5 | 228.20 g/mol
Supplier: Thermo Scientific Chemicals A1602603
Description
2'-Deoxyuridine is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2?-Deoxyuridines used as labeling substrates include chloro-2?-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). Other useful analogues of 2?-deoxyuridine include 5-ethynyl-2?-deoxyuridine (DdU) and 5-hydroxymethyl-2?-deoxyuridine (HmdU). Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies. Deoxyuridine (dU) is used to indirectly determine if there are sufficient levels of folate and cobalamin in cell or tissue samples.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications2′-Deoxyuridine is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2′-Deoxyuridines used as labeling substrates include chloro-2′-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). Other useful analogues of 2′-deoxyuridine include 5-ethynyl-2′-deoxyuridine (DdU) and 5-hydroxymethyl-2′-deoxyuridine (HmdU). Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies. Deoxyuridine (dU) is used to indirectly determine if there are sufficient levels of folate and cobalamin in cell or tissue samples.
Solubility
Soluble in water.
Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is sensitive to air.
Greener Choice Claims
- Environmental benefits include:
- Free-of a substance that causes environmental harm
Specifications
| 2'-Deoxyuridine | |
| 164°C to 167°C | |
| MFCD00006527 | |
| 24433 | |
| 14,2910 | |
| Soluble in water. | |
| +52° (c=1.1 in 1N NaOH) | |
| 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione | |
| 13712 | |
| 228.21 |
| 951-78-0 | |
| C9H12N2O5 | |
| 1 g | |
| Air Sensitive | |
| 2'-deoxyuridine, deoxyuridine, uracil deoxyriboside, 2-deoxyuridine, 1-2r,4s,5r-4-hydroxy-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidine-2,4 1h,3h-dione, deoxyribose uracil, uridine, 2'-deoxy, 2'-desoxyuridine, unii-w78i7ay22c, ccris 2832 | |
| MXHRCPNRJAMMIM-SHYZEUOFSA-N | |
| OC[C@H]1O[C@H](C[C@@H]1O)N1C=CC(=O)NC1=O | |
| 228.20 | |
| CHEBI:16450 | |
| 99% |
Chemical Identifiers
| 951-78-0 | |
| 228.20 | |
| MXHRCPNRJAMMIM-SHYZEUOFSA-N | |
| 13712 | |
| 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
| C9H12N2O5 | |
| MFCD00006527 | |
| 2'-deoxyuridine, deoxyuridine, uracil deoxyriboside, 2-deoxyuridine, 1-2r,4s,5r-4-hydroxy-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidine-2,4 1h,3h-dione, deoxyribose uracil, uridine, 2'-deoxy, 2'-desoxyuridine, unii-w78i7ay22c, ccris 2832Show More | |
| CHEBI:16450 | |
| OC[C@H]1O[C@H](C[C@@H]1O)N1C=CC(=O)NC1=O |
Safety and Handling
EINECSNumber : 213-455-7
RTECSNumber : YU7490000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only