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  6. Sigma Aldrich 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite

Sigma Aldrich 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite

Catalog No. 3059955G
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3059955G 5 g
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Catalog No. 3059955G Supplier Sigma Aldrich Supplier No. 3059955G
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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

  • 2-cyanoethyl n,n,nα,nα-tetraisopropylphosphordiamidite was used:
  • In preparation of prosphoramidite reagent, required for synthesis of 12-mer oligodeoxynucleotide
  • As phosphorylating agent in synthesis of 1,2-diacyl-sn-glycerophosphatidylserine
  • In situ preparation of deoxyribonucleoside phosphoramidites
  • In preparation of 2α-deoxy-2α-fluoro-3α-o-(α-cyanoethyl-n,n-diisopropylphosphoramidic)-5α-o-(4-methoxytrityl)-4α-thio-α-d-arabinouridine and 1-(3-o-(α-cyanoethyl-n,n-diisopropylphosphoramidic)-2-deoxy-2-fluoro-5-o-(4,4α-dimethoxytrityl)-4-thio-α-d-arabinofuranosyl)-thymine
  • As reagent for synthesizing phosphitylated nucleotides

Specifications

CAS 102691-36-1
Density 0.949 g/mL (at 25°C (literature))
Boiling Point 100°C (0.5 mmHg)
Molecular Formula C15H32N3OP
Refractive Index n20/D 1.470 (literature)
Linear Formula {[(CH3)2 CH]2 N}2 POCH2CH2CN
MDL Number MFCD00012213
Quantity 5 g
Synonym Bis(diisopropylamino)(2-cyanoethoxy)phosphine
Molecular Weight (g/mol) 301.41
Percent Purity 97%
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