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  7. 1-Trimethylsilylmethanol, 95%

1-Trimethylsilylmethanol, 95%

Catalog No. p-7058288
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AAL0425103 1 g
AAL0425106 5 g
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Catalog No. AAL0425103 Supplier Thermo Scientific Chemicals Supplier No. L0425103
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Description

CAS: 3219-63-4 | C4H12OSi | 104.224 g/mol

1-Trimethylsilylmethanol is used as nucleophile to resolve the racemate obtained from enantioselective esterification of naproxen (2-(6-methoxy-2-naphthyl) propionic acid) by lipases. It was also used as a nucleophilic hydroxymethylation agent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Trimethylsilylmethanol is used as nucleophile to resolve the racemate obtained from enantioselective esterification of naproxen (2-(6-methoxy-2-naphthyl) propionic acid) by lipases. It was also used as a nucleophilic hydroxymethylation agent.

Solubility
Fully miscible in water.

Notes
Store at 4°C. Incompatible with oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Chemical Identifiers

CAS 3219-63-4
Molecular Formula C4H12OSi
Molecular Weight (g/mol) 104.224
MDL Number MFCD00004596
InChI Key ZQKNBDOVPOZPLY-UHFFFAOYSA-N
Synonym trimethylsilyl methanol, 1-trimethylsilylmethanol, hydroxymethyltrimethylsilane, methanol, trimethylsilyl, silane, hydroxymethyl trimethyl, hydroxymethyl trimethylsilane, trimethylhydroxymethylsilane, methanol, 1-trimethylsilyl, trimethylsilyl-methanol, acmc-209hrr
PubChem CID 76692
IUPAC Name trimethylsilylmethanol
SMILES C[Si](C)(C)CO

Specifications

Boiling Point 121°C to 122°C
Quantity 1 g
UN Number UN1993
Beilstein 1731486
Flash Point 31°C (87°F)
Solubility Information Fully miscible in water.
Formula Weight 104.23
Percent Purity ≥98%
Refractive Index 1.419
Density 0.827
Chemical Name or Material 1-Trimethylsilylmethanol
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Safety and Handling

Hazard Category H226
Hazard Statement GHS H Statement
H226
Flammable liquid and vapor.
Precautionary Statement P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378q-P501c
DOTInformation Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, N.O.S.
EINECSNumber 221-746-5
RTECSNumber PC4100000
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only