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1-Methylpiperazine, 98+%

CAS: 109-01-3 | C5H12N2 | 100.165 g/mol

$67.08 - $909.14

Chemical Identifiers

CAS 109-01-3
Molecular Formula C5H12N2
Molecular Weight (g/mol) 100.165
MDL Number MFCD00005966
InChI Key PVOAHINGSUIXLS-UHFFFAOYSA-N
Synonym n-methylpiperazine, piperazine, 1-methyl, 4-methylpiperazine, 1-methyl-piperazine, n-methyl piperazine, 1-methyl piperazine, methylpiperazine, n-methyl-piperazine, n-methylpiperazin, 1-methylpyperazine
PubChem CID 53167
IUPAC Name 1-methylpiperazine
SMILES CN1CCNCC1
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Products 3
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAA10837AE
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Thermo Scientific Chemicals
A10837AE
100 mL
Each for $67.08
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AAA10837AP
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Thermo Scientific Chemicals
A10837AP
500 mL
Each for $238.32
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AAA108370F
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Thermo Scientific Chemicals
A108370F
2500 mL
Each for $909.14
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Description

Description

1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.

Solubility
Miscible with water and methanol.

Notes
Hygroscopic. Moisture sensitive. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents and carbon dioxide.
Specifications

Chemical Identifiers

109-01-3
100.165
PVOAHINGSUIXLS-UHFFFAOYSA-N
53167
CN1CCNCC1
C5H12N2
MFCD00005966
n-methylpiperazine, piperazine, 1-methyl, 4-methylpiperazine, 1-methyl-piperazine, n-methyl piperazine, 1-methyl piperazine, methylpiperazine, n-methyl-piperazine, n-methylpiperazin, 1-methylpyperazine
1-methylpiperazine

Specifications

109-01-3
0.903
34°C (93°F)
C5H12N2
MFCD00005966
UN2734
Air Sensitive
Miscible with water and methanol.
CN1CCNCC1
100.165
100.17
1-Methylpiperazine
-6°C
137°C to 139°C
Amine-like
1.4655
100 mL
102724
n-methylpiperazine, piperazine, 1-methyl, 4-methylpiperazine, 1-methyl-piperazine, n-methyl piperazine, 1-methyl piperazine, methylpiperazine, n-methyl-piperazine, n-methylpiperazin, 1-methylpyperazine
PVOAHINGSUIXLS-UHFFFAOYSA-N
1-methylpiperazine
53167
≥98%
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Safety and Handling

Safety and Handling

GHS H Statement
H331-H314-H318-H226-H302-H312
Toxic if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapor.
Harmful if swallowed.
Harmful in contact with skin.

P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P272-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P370+P378q-P501c

H226-H302+H312+H332-H314-H317-H335

DOTInformation : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: AMINES, LIQUID, CORROSIVE, FLAMMABLE, N.O.S.

EINECSNumber : 203-639-5

RTECSNumber : TM1225000

TSCA : Yes

Recommended Storage : Ambient temperatures; Store under Argon

SDS
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RUO – Research Use Only