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1-Methyl-1H-pyrazole-4-boronic acid pinacol ester, 97%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals H5313903
Description
It is a reagent used for Suzuki-Miyaura cross-coupling reactions, transesterification reactions. It is involved in several reactions as a reagent for the preparation of aminothiazoles as γ-secretase modulators,amino-pyrido-indol-carboxamides, as potential JAK2 inhibitors for myeloproliferative disorders therapy, pyridine derivatives as TGF-β1 and active A signaling inhibitors and MK-2461 analogs as inhibitors of c-Met kinase for the treatment of cancer.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsIt is a reagent used for Suzuki-Miyaura cross-coupling reactions, transesterification reactions. It is involved in several reactions as a reagent for the preparation of aminothiazoles as γ-secretase modulators,amino-pyrido-indol-carboxamides, as potential JAK2 inhibitors for myeloproliferative disorders therapy, pyridine derivatives as TGF-β1 and active A signaling inhibitors and MK-2461 analogs as inhibitors of c-Met kinase for the treatment of cancer.
Solubility
Slightly soluble in water.
Notes
Store in cool dry place. Ensure proper ventilation. Incompatible with oxidizing agents.
Specifications
| 1-Methyl-1H-pyrazole-4-boronic acid pinacol ester | |
| 59°C to 64°C | |
| MFCD03789259 | |
| 1-methyl-4-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl-1h-pyrazole, 1-methylpyrazole-4-boronic acid pinacol ester, 1-methyl-4-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl pyrazole, 1-methyl-1h-pyrazole-4-boronic acid pinacol ester, 1-methyl-4-tetramethyl-1,3,2-dioxaborolan-2-yl-1h-pyrazole, 1-methyl-pyrazole-4-boronic acid pinacol ester, 1-methyl-4-4,4,5,5-tetramethyl-1,3,2 dioxaborolan-2-yl-1h-pyrazole, 1h-pyrazole, 1-methyl-4-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl, 1-methyl-4-tetramethyl-1,3,2-dioxaborolan-2-yl pyrazole, 1-methyl-4-pyrazoleboronic acid pinacol ester | |
| UCNGGGYMLHAMJG-UHFFFAOYSA-N | |
| 1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole | |
| 2773987 | |
| 97% |
| 761446-44-0 | |
| C10H17BN2O2 | |
| 1 g | |
| Slightly soluble in water. | |
| CN1C=C(C=N1)B1OC(C)(C)C(C)(C)O1 | |
| 208.07 | |
| 208.07 |
Chemical Identifiers
| 761446-44-0 | |
| 208.07 | |
| UCNGGGYMLHAMJG-UHFFFAOYSA-N | |
| 2773987 | |
| CN1C=C(C=N1)B1OC(C)(C)C(C)(C)O1 |
| C10H17BN2O2 | |
| MFCD03789259 | |
| 1-methyl-4-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl-1h-pyrazole, 1-methylpyrazole-4-boronic acid pinacol ester, 1-methyl-4-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl pyrazole, 1-methyl-1h-pyrazole-4-boronic acid pinacol ester, 1-methyl-4-tetramethyl-1,3,2-dioxaborolan-2-yl-1h-pyrazole, 1-methyl-pyrazole-4-boronic acid pinacol ester, 1-methyl-4-4,4,5,5-tetramethyl-1,3,2 dioxaborolan-2-yl-1h-pyrazole, 1h-pyrazole, 1-methyl-4-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl, 1-methyl-4-tetramethyl-1,3,2-dioxaborolan-2-yl pyrazole, 1-methyl-4-pyrazoleboronic acid pinacol ester | |
| 1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole |
Safety and Handling
GHS H Statement
H301-H315-H319-H335
Toxic if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
H315-H319-H335
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only