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1,4-Dithio-DL-threitol, Electrophoresis Grade, 99%
CAS: 3483-12-3 | C4H10O2S2 | 154.24 g/mol
$86.33 - $886.18
Chemical Identifiers
| CAS | 12-3-3483 |
|---|---|
| Molecular Formula | C4H10O2S2 |
| Molecular Weight (g/mol) | 154.24 |
| MDL Number | MFCD00004877 |
| InChI Key | VHJLVAABSRFDPM-IMJSIDKUSA-N |
| Synonym | dithiothreitol, dl-1,4-dithiothreitol, dl-dithiothreitol, 1,4-dithio-dl-threitol, d-1,4-dithiothreitol, d-dtt, 2s,3s-1,4-dimercaptobutane-2,3-diol, threo-1,4-dimercapto-2,3-butanediol, 1,4-dithiothreitol, dtt |
| PubChem CID | 446094 |
| ChEBI | CHEBI:42170 |
| IUPAC Name | (2S,3S)-1,4-bis(sulfanyl)butane-2,3-diol |
| SMILES | C(C(C(CS)O)O)S |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ6454503
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Thermo Scientific Chemicals
J6454503 |
1 g |
Each for $86.33
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AAJ6454506
|
Thermo Scientific Chemicals
J6454506 |
5 g |
Each for $225.96
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AAJ6454514
|
Thermo Scientific Chemicals
J6454514 |
25 g |
Each for $886.18
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Description
1,4-Dithio-DL-threitol is used as a protective agent for preventing oxidation of thiol groups and reagent for the reduction of disulfide groups in proteins. It is employed to investigate a-ketoglutarate dehydrogenase function, flavin cofactors in proteins and protein moieties involved in peroxide reduction. It is also useful for stabilizing sulfhydryl-containing enzymes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications1,4-Dithio-DL-threitol is used as a protective agent for preventing oxidation of thiol groups and reagent for the reduction of disulfide groups in proteins. It is employed to investigate a-ketoglutarate dehydrogenase function, flavin cofactors in proteins and protein moieties involved in peroxide reduction. It is also useful for stabilizing sulfhydryl-containing enzymes.
Solubility
Soluble in water, ethanol, chloroform, diethyl ether, acetone, ether and ethyl acetate.
Notes
Air and heat sensitive. Hygroscopic. Incompatible with strong oxidizing agents, reducing agents and alkalies.
Chemical Identifiers
| 12-3-3483 | |
| 154.24 | |
| VHJLVAABSRFDPM-IMJSIDKUSA-N | |
| 446094 | |
| (2S,3S)-1,4-bis(sulfanyl)butane-2,3-diol |
| C4H10O2S2 | |
| MFCD00004877 | |
| dithiothreitol, dl-1,4-dithiothreitol, dl-dithiothreitol, 1,4-dithio-dl-threitol, d-1,4-dithiothreitol, d-dtt, 2s,3s-1,4-dimercaptobutane-2,3-diol, threo-1,4-dimercapto-2,3-butanediol, 1,4-dithiothreitol, dtt | |
| CHEBI:42170 | |
| C(C(C(CS)O)O)S |
Specifications
| 12-3-3483 | |
| White | |
| >110°C (230°F) | |
| C4H10O2S2 | |
| 1 g | |
| Air sensitive | |
| dithiothreitol, dl-1,4-dithiothreitol, dl-dithiothreitol, 1,4-dithio-dl-threitol, d-1,4-dithiothreitol, d-dtt, 2s,3s-1,4-dimercaptobutane-2,3-diol, threo-1,4-dimercapto-2,3-butanediol, 1,4-dithiothreitol, dtt | |
| VHJLVAABSRFDPM-IMJSIDKUSA-N | |
| (2S,3S)-1,4-bis(sulfanyl)butane-2,3-diol | |
| 446094 | |
| 154.25 | |
| Electrophoresis | |
| 1,4-Dithio-DL-threitol |
| 40°C to 43°C | |
| 125°C to 130°C (12 mmHg) | |
| Unpleasant | |
| MFCD00004877 | |
| 1719757 | |
| 14,3376 | |
| Soluble in water,ethanol,chloroform,diethyl ether,acetone,ether and ethyl acetate. | |
| C(C(C(CS)O)O)S | |
| 154.24 | |
| CHEBI:42170 | |
| 99% | |
| Powder |
Safety and Handling
GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302-H315-H319-H335
EINECSNumber : 222-468-7
RTECSNumber : EK1610000
TSCA : Yes
Recommended Storage : Keep cold
RUO – Research Use Only