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1,4-Dithio-DL-threitol, 98%
CAS: 3483-12-3 | C4H10O2S2 | 154.24 g/mol
Supplier: Thermo Scientific Chemicals A1579714
Description
Useful for stabilizing sulfhydryl-containing enzymes1,4-Dithio-DL-threitol is used as a protective agent in preventing oxidation of thiol groups and reagent for the reduction of disulfide groups in proteins. It is employed to investigate a-ketoglutarate dehydrogenase function, flavin cofactors in proteins and protein moieties involved in peroxide reduction. It is also useful for stabilizing sulfhydryl-containing enzymes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsUseful for stabilizing sulfhydryl-containing enzymes1,4-Dithio-DL-threitol is used as a protective agent in preventing oxidation of thiol groups and reagent for the reduction of disulfide groups in proteins. It is employed to investigate a-ketoglutarate dehydrogenase function, flavin cofactors in proteins and protein moieties involved in peroxide reduction. It is also useful for stabilizing sulfhydryl-containing enzymes.
Solubility
Soluble in water, ethanol, chloroform, diethyl ether, acetone, ether and ethyl acetate.
Notes
Air sensitive and hygroscopic. Store in a cool place. Incompatible with strong oxidizing agents, reducing agents and alkalies.
Specifications
| 1,4-Dithio-DL-threitol | |
| 40°C to 43°C | |
| >110°C (230°F) | |
| C4H10O2S2 | |
| 25 g | |
| Air sensitive | |
| dithiothreitol, dl-1,4-dithiothreitol, dl-dithiothreitol, 1,4-dithio-dl-threitol, d-1,4-dithiothreitol, d-dtt, 2s,3s-1,4-dimercaptobutane-2,3-diol, threo-1,4-dimercapto-2,3-butanediol, 1,4-dithiothreitol, dtt | |
| VHJLVAABSRFDPM-IMJSIDKUSA-N | |
| (2S,3S)-1,4-bis(sulfanyl)butane-2,3-diol | |
| 446094 | |
| 154.25 |
| 12-3-3483 | |
| 125°C to 130°C (12 mmHg) | |
| Unpleasant | |
| MFCD00004877 | |
| 1719757 | |
| 14,3376 | |
| Soluble in water,ethanol,chloroform,diethyl ether,acetone,ether and ethyl acetate. | |
| C(C(C(CS)O)O)S | |
| 154.24 | |
| CHEBI:42170 | |
| 98% |
Chemical Identifiers
| 12-3-3483 | |
| 154.24 | |
| VHJLVAABSRFDPM-IMJSIDKUSA-N | |
| 446094 | |
| (2S,3S)-1,4-bis(sulfanyl)butane-2,3-diol |
| C4H10O2S2 | |
| MFCD00004877 | |
| dithiothreitol, dl-1,4-dithiothreitol, dl-dithiothreitol, 1,4-dithio-dl-threitol, d-1,4-dithiothreitol, d-dtt, 2s,3s-1,4-dimercaptobutane-2,3-diol, threo-1,4-dimercapto-2,3-butanediol, 1,4-dithiothreitol, dtt | |
| CHEBI:42170 | |
| C(C(C(CS)O)O)S |
Safety and Handling
GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302-H315-H319-H335
EINECSNumber : 222-468-7
RTECSNumber : EK1610000
TSCA : Yes
Recommended Storage : Keep cold; Store under Argon
RUO – Research Use Only