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1-(2-Aminoethyl)piperidine, 98%

Catalog No. p-7024138
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Quantity:
25 g
5 g
Catalog No. Quantity
AAA1837306 5 g
AAA1837314 25 g
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Catalog No. AAA1837306

Supplier: Thermo Scientific Chemicals A1837306

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CAS: 27578-60-5 | C7H16N2 | 128.219 g/mol

1-(2-Aminoethyl)piperidine is used in modification of vinylbenzyl chloride/divinylbenzene gel copolymer bead and in the synthesis of linkage isomers trans-bis[1-(2-aminoethyl)piperidine]dinitronickel and trans-bis[1-(2-aminoethyl)-piperidine]dinitritonickel. It is also used as a reactant for synthesis of: analogs of anticancer agents, inhibitor of botulinum neurotoxin serotype A light chain, P. falciparum malaria, and Ebola filovirus, cannabinoid CB1 receptor antagonists, small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells, potent and selective 5-HT6 antagonists and N-mustards as anticancer agents. 1-(2-Aminoethyl)piperidine on [1+1] condensation reaction with 3-methoxy salicylaldehyde yields tridentate Schiff base ligand.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(2-Aminoethyl)piperidine is used in modification of vinylbenzyl chloride/divinylbenzene gel copolymer bead and in the synthesis of linkage isomers trans-bis[1-(2-aminoethyl)piperidine]dinitronickel and trans-bis[1-(2-aminoethyl)-piperidine]dinitritonickel. It is also used as a reactant for synthesis of: analogs of anticancer agents, inhibitor of botulinum neurotoxin serotype A light chain, P. falciparum malaria, and Ebola filovirus, cannabinoid CB1 receptor antagonists, small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells, potent and selective 5-HT6 antagonists and N-mustards as anticancer agents. 1-(2-Aminoethyl)piperidine on [1+1] condensation reaction with 3-methoxy salicylaldehyde yields tridentate Schiff base ligand.

Solubility
Partly miscible in water.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents, acid chlorides and acid anhydrides. It is sensitive to air.

Chemical Identifiers

CAS 27578-60-5
Molecular Formula C7H16N2
Molecular Weight (g/mol) 128.219
MDL Number MFCD00006516
InChI Key CJNRGSHEMCMUOE-UHFFFAOYSA-N
Synonym n-2-aminoethyl piperidine, 1-2-aminoethyl piperidine, 2-piperidin-1-yl ethanamine, 2-piperidin-1-yl ethan-1-amine, 1-piperidineethanamine, 2-piperidinoethylamine, 2-1-piperidinyl ethanamine, 2-1-piperidinyl ethylamine, n-aminoethylpiperidine, 2-piperidino-1-ethanamine
PubChem CID 33944
IUPAC Name 2-piperidin-1-ylethanamine
SMILES C1CCN(CC1)CCN

Specifications

Density 0.903
Boiling Point 185°C to 186°C
Flash Point 57°C (134°F)
Refractive Index 1.474
Quantity 5 g
UN Number UN2733
Beilstein 103469
Sensitivity Air Sensitive
Solubility Information Partly miscible in water.
Formula Weight 128.22
Percent Purity 98%
Chemical Name or Material 1-(2-Aminoethyl)piperidine
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Hazard Category H226-H314
Hazard Statement GHS H Statement
H314-H318-H226
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapour.
Precautionary Statement P210-P233-P240-P241-P242-P243-P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: AMINES, FLAMMABLE, CORROSIVE, N.O.S.
EINECSNumber 248-540-8
TSCA No
Recommended Storage Ambient temperatures

RUO – Research Use Only