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1,2,2,6,6-Pentamethylpiperidine, 97%

Catalog No. AAH2772903
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Catalog No. AAH2772903 Supplier Thermo Scientific Chemicals Supplier No. H2772903
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Description

CAS: 79-55-0 | C10H21N | 155.285 g/mol

Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine's ED50 4.7-fold.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Pharmacological evaluation of the antagonism of nicotine′s central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine′s ED50 4.7-fold.

Solubility
Soluble in toluene, dimethylformamide.

Notes
Air Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air.

Chemical Identifiers

CAS 79-55-0
Molecular Formula C10H21N
Molecular Weight (g/mol) 155.285
MDL Number MFCD00006493
InChI Key XULIXFLCVXWHRF-UHFFFAOYSA-N
Synonym pempidine, pyrilene, perolysen, tenormal, piperidine, 1,2,2,6,6-pentamethyl, pempidina dcit, pempidine inn:ban, pempidinum inn-latin, unii-n5i18ji9d6, 1,2,2,6,6-pentamethyl-piperidine
PubChem CID 6603
IUPAC Name 1,2,2,6,6-pentamethylpiperidine
SMILES CC1(CCCC(N1C)(C)C)C

Specifications

Density 0.858
Boiling Point 187°C to 188°C
Flash Point 50°C (122°F)
Odor Amine-like
Quantity 1 g
UN Number UN1992
Beilstein 103806
Sensitivity Air Sensitive
Merck Index 14,7080
Solubility Information Soluble in toluene,dimethylformamide.
Formula Weight 155.28
Percent Purity 97%
Chemical Name or Material 1,2,2,6,6-Pentamethylpiperidine
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Safety and Handling

Hazard Category H226-H301-H315-H319-H335
Hazard Statement GHS H Statement
H226-H302-H315-H319-H335
Flammable liquid and vapor.
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P210-P233-P235-P240-P241-P242-P243-P261-P264b-P270-P271-P280-P301+P310-P303+P361+P353-P304+P340-P305+P351+P338-P312-P330-P332+P313-P363-P370+P378q-P501c
DOTInformation Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, TOXIC, N.O.S.
EINECSNumber 201-211-2
RTECSNumber TN2190000
TSCA Yes
Recommended Storage Ambient temperatures; Store under Nitrogen

RUO – Research Use Only