missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

1,1-Dimethylbiguanide hydrochloride, Thermo Scientific Chemicals

1,1-Dimethylbiguanide hydrochloride (metformin hydrochloride, CAS # 115-70-4) is the salt of methylated biguanide, a compound exhibiting anti-hyperglycemic properties.

$79.99 - $551.51

Chemical Identifiers

CAS 1115-70-4
Molecular Formula C4H12ClN5
Molecular Weight (g/mol) 165.63
MDL Number MFCD00012582
InChI Key OETHQSJEHLVLGH-UHFFFAOYSA-N
Synonym metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform
PubChem CID 14219
IUPAC Name hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride
SMILES [H+].[Cl-].CN(C)C(=N)N=C(N)N
View More Specs

Products 3
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ6336106
View Documents
Thermo Scientific Chemicals
J6336106
5 g
Each for $79.99
 
AAJ6336114
View Documents
Thermo Scientific Chemicals
J6336114
25 g
Each for $199.05
 
AAJ6336122
View Documents
Thermo Scientific Chemicals
J6336122
100 g
Each for $551.51
 
Description

Description

1,1-Dimethylbiguanide hydrochloride is used as an antidiabetic agent, used in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2. It may also reduce weight gain in people taking atypical antipsychotics, used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• 1,1-Dimethylbiguanide consists of two guanidines with methyl substitutions at position 1

• 1,1-Dimethylbiguanide hydrochloride inhibits complex I of the mitochondrial respiratory chain, increasing AMP and activating target genes

• 1,1-Dimethylbiguanide hydrochloride enhances insulin sensitivity and fatty acid oxidation in cells

• 1,1-Dimethylbiguanide hydrochloride may also have antineoplastic action through the mammalian target of rapamycin pathway

• It is suitable for the laboratory research of diabetes, obesity, and related metabolic disorders

• It is also useful for the laboratory study of mammalian target of rapamycin (mTOR) pathways and AMPK ratios within the cell

Specifications

Chemical Identifiers

1115-70-4
165.63
OETHQSJEHLVLGH-UHFFFAOYSA-N
14219
[H+].[Cl-].CN(C)C(=N)N=C(N)N
C4H12ClN5
MFCD00012582
metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform
hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride

Specifications

1115-70-4
White
NH2C(=NH)NHC(=NH)N(CH3)2·HCl
5 g
metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform
OETHQSJEHLVLGH-UHFFFAOYSA-N
hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride
14219
Powder
218°C to 226°C
C4H12ClN5
MFCD00012582
14,5938
Soluble in water (50mg/ml),ethanol,and DMSO (50 mM).
[H+].[Cl-].CN(C)C(=N)N=C(N)N
165.63
165.62
1,1-Dimethylbiguanide hydrochloride
Videos
Safety and Handling

Safety and Handling

GHS H Statement
H302-H315-H319
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.

P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c

H302-H315-H319-H335

EINECSNumber : 214-230-6

RTECSNumber : DU1800000

TSCA : No

Recommended Storage : Keep cold

SDS
missing translation for 'documents'

missing translation for 'documents'

RUO – Research Use Only