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New Innovative Technology 2025, Issue 2

Labconco CentriVap Pro: A Step-by-Step Configuration Guide

December 2025 | 3 min read | By: Labconco
Labconco CentriVap Pro: A Step-by-Step Configuration Guide

If you’re looking to supercharge your sample prep workflow, selecting the perfect Labconco CentriVap Pro Vacuum Concentrator setup is the first step in optimizing your research. Walk through the process of configuring a CentriVap Pro system tailored to your specific applications.

Step 1: Identify Your Application Needs

Before diving into configuration, it’s crucial to assess your laboratory’s specific requirements. Labconco offers a wide range of concentrators, rotors, and accessories to suit your lab’s needs. Consider the following questions:

What is your sample volume?

The CentriVap Pro and Standard CentriVap can handle samples up to 50 mL per container with a wide variety of rotor options for most standard vials, tubes, and microplates.

Are your samples heat sensitive?

For heat-sensitive samples like RNA and proteins, the Refrigerated CentriVap Pro cools to –10°C and warms to +100°C.

What solvents will you be using?

For corrosive solvents, an acid-resistant configuration with a PTFE-coated chamber, glass lid, and chemically compatible vacuum pump is recommended.

Do you need to monitor samples during a run?

The CentriZap Pro Strobe Light allows you to view samples without pausing the run.

Step 2: Choose Your CentriVap Pro Model

Labconco offers six main concentrator configurations:

CentriVap Pro: Ideal for general-purpose laboratory concentration.

Refrigerated CentriVap Pro: Essential for heat-sensitive samples, maintaining optimal temperatures between—10°C and +100°C using an environmentally friendly natural refrigerant.

Acid Resistant CentriVap Pro: Designed for processing corrosive chemicals such as hydrochloric acid, acetic acid, or sodium hydroxide, it includes a PTFE-coated chamber, Hastelloy drive shaft, ceramic bearings, and a glass lid.

DNA CentriVap Pro: An all-in-one solution ready to process your samples right out of the box with a built-in diaphragm vacuum pump, integrated glass traps, and a stainless-steel DNA rotor.

Standard CentriVap: A simplified model for those who don’t need advanced features and maximum throughput.

Standard DNA CentriVap: A simplified all-in-one model for those who don’t need advanced features and maximum throughput.

All CentriVap Pro models feature VaporWorks OS, which allows you to customize and store a library of run parameters, log and export run data, and perform device diagnostics.

Step 3: Select Your Rotors

Labconco offers a wide range of rotors to accommodate various sample sizes and vessel types. After matching your sample containers with the proper rotor style, rotors can be further optimized with an acid-resistant PTFE coating. For high-throughput applications, Labconco’s DNA, Hex, 15 x 45 mm, and High-Capacity Pro rotors can be stacked to double sample processing capabilities.

Step 4: Select a Cold Trap

A cold trap is essential for protecting your vacuum pump by collecting evaporated solvents. Labconco offers a range of cold traps to suit different solvents:

  • –50°C Cold Trap: Suitable for most common aqueous samples
  • –84°C Cold Traps: Recommended for low-freezing-point solvents like acetonitrile and chloroform
  • –105°C Cold Traps: Recommended for solvents like dilute methanol and ethanol

Step 5: Select a Vacuum Pump

Labconco offers Diaphragm Vacuum Pumps optimized for the CentriVap Pro. These pumps offer moderate chemical resistance in a small footprint. For applications requiring lower vacuum pressure, a Rotary Vane or Hybrid Vacuum Pump can be used.

Step 6: Choose Your Accessories

You can further enhance your CentriVap Pro System with optional accessories, including the CentriZap Strobe Light, the CentriVap Cart, secondary traps, and a cold trap manifold.

By carefully considering your laboratory’s needs and following this step-by-step guide, you can configure a Labconco CentriVap Pro system that optimizes your sample concentration workflow and accelerates your research.

For more information, please visit fishersci.ca/labconco or contact your Fisher Scientific sales representative.

Content provided by: Labconco